Anti-CD22, Recombinant [RFB-4]
Invented at Absolute Antibody University College London
Anti-CD22 [RFB-4]
Invented at University College London
- Datasheet
- References (8)
- Inventor Info
Info
| Catalogue Number | 151335 |
| Applications | FACS IHC IF |
| Antigen/Gene or Protein Targets | CD22 |
| Reactivity | Human |
| Relevance | Establishing origin of B cell malignancies, especially discriminating between immature (bone marrow type) and peripheral B cell leukaemias and lymphomas. Suitable for use as an immunotoxin against human B cell leukaemias and lymphomas. |
| Host | Mouse |
| Immunogen | Tonsil lymphocytes |
| Subclass | IgG1 |
| Molecular Weight (kDa) | 153 |
| Myeloma Used | P3X63Ag8 |
| Recommended Growing Conditions | DMEM + 5% FCS |
| Strain | Balb/c |
| Notes | Cytoplasmic antigen of mature B lymphocytes. >90% reactivity on peripheral B cells. |
| Research Area | Adhesion, Cancer, Cell Signaling & Signal Transduction, Immunology, Stem Cell Biology |
References: 8 entries
DiJoseph et al. 2006. Clin Cancer Res. 12(1):242-9. PMID: 16397048.
Antitumor efficacy of a combination of CMC-544 (inotuzumab ozogamicin), a CD22-targeted cytotoxic immunoconjugate of calicheamicin, and rituximab against non-Hodgkin's B-cell lymphoma.
Europe PMC ID: 16397048
Shen et al. 1988. Int J Cancer. 42(5):792-7. PMID: 3263328.
Evaluation of four CD22 antibodies as ricin A chain-containing immunotoxins for the in vivo therapy of human B-cell leukemias and lymphomas.
Europe PMC ID: 3263328
Bofill et al. 1985. J Immunol. 134(3):1531-8. PMID: 3871452.
Campana et al. 1985. J Immunol. 134(3):1524-30. PMID: 3918103.
Human B cell development. II. Subpopulations in the human fetus.
Europe PMC ID: 3871452
Human B cell development. I. Phenotypic differences of B lymphocytes in the bone marrow and peripheral lymphoid tissue.
Europe PMC ID: 3918103
Add a reference
References: 8 entries
DiJoseph et al. 2006. Clin Cancer Res. 12(1):242-9. PMID: 16397048.
Antitumor efficacy of a combination of CMC-544 (inotuzumab ozogamicin), a CD22-targeted cytotoxic immunoconjugate of calicheamicin, and rituximab against non-Hodgkin's B-cell lymphoma.
Shen et al. 1988. Int J Cancer. 42(5):792-7. PMID: 3263328.
Evaluation of four CD22 antibodies as ricin A chain-containing immunotoxins for the in vivo therapy of human B-cell leukemias and lymphomas.
Bofill et al. 1985. J Immunol. 134(3):1531-8. PMID: 3871452.
Campana et al. 1985. J Immunol. 134(3):1524-30. PMID: 3918103.
Human B cell development. II. Subpopulations in the human fetus.
Human B cell development. I. Phenotypic differences of B lymphocytes in the bone marrow and peripheral lymphoid tissue.
Add a reference
