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Anti-TAF15 [8TA-2B10]

Info

Applications ELISA IF IP WB
Antigen/Gene or Protein Targets TAF15/TAFII 68 
Reactivity Human
Relevance TAF15 is a member of the TET family of RNA-binding proteins. It plays a role in RNA polymerase II gene transcription as a component of a distinct subset of multi-subunit transcription initiation factor TFIID complexes. Translocations involving this gene play a role in acute leukemia and extraskeletal myxoid chondrosarcoma, and mutations in this gene may play a role in amyotrophic lateral sclerosis.
Host Mouse
Immunogen The RNA-binding region (RNP) of human TAF15/TAFII68 as a GST-fusion protein (from amino acid 175 to 414).
Subclass IgG1 kappa
Notes Available in 100ul units

Recommended dilution: 1/500-1/5000
Research Area Epigenetics & Nuclear Signalling

References: 4 entries

Bertolotti et al. 1998. Mol Cell Biol. 18(3):1489-97. PMID: 9488465.

EWS, but not EWS-FLI-1, is associated with both TFIID and RNA polymerase II: interactions between two members of the TET family, EWS and hTAFII68, and subunits of TFIID and RNA polymerase II complexes.

Europe PMC ID: 9488465

Bertolotti et al. 1996. EMBO J. 15(18):5022-31. PMID: 8890175.

hTAF(II)68, a novel RNA/ssDNA-binding protein with homology to the pro-oncoproteins TLS/FUS and EWS is associated with both TFIID and RNA polymerase II.

Europe PMC ID: 8890175


Add a reference

References: 4 entries

Bertolotti et al. 1998. Mol Cell Biol. 18(3):1489-97. PMID: 9488465.

EWS, but not EWS-FLI-1, is associated with both TFIID and RNA polymerase II: interactions between two members of the TET family, EWS and hTAFII68, and subunits of TFIID and RNA polymerase II complexes.

Europe PMC ID: 9488465

Bertolotti et al. 1996. EMBO J. 15(18):5022-31. PMID: 8890175.

hTAF(II)68, a novel RNA/ssDNA-binding protein with homology to the pro-oncoproteins TLS/FUS and EWS is associated with both TFIID and RNA polymerase II.

Europe PMC ID: 8890175


Add a reference

References: 4 entries

Bertolotti et al. 1998. Mol Cell Biol. 18(3):1489-97. PMID: 9488465.

EWS, but not EWS-FLI-1, is associated with both TFIID and RNA polymerase II: interactions between two members of the TET family, EWS and hTAFII68, and subunits of TFIID and RNA polymerase II complexes.

Bertolotti et al. 1996. EMBO J. 15(18):5022-31. PMID: 8890175.

hTAF(II)68, a novel RNA/ssDNA-binding protein with homology to the pro-oncoproteins TLS/FUS and EWS is associated with both TFIID and RNA polymerase II.


Add a reference


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