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Anti-POLR2A [1PB-7E11]

Info

Applications ELISA IF WB
Antigen/Gene or Protein Targets  RNA Polymerase B Subunit hRPB1
Reactivity Human
Relevance POLR2A is the largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The protein contains a carboxy terminal domain composed of heptapeptide repeats that are essential for polymerase activity. These repeats contain serine and threonine residues that are phosphorylated in actively transcribing RNA polymerase. In addition, this subunit, in combination with several other polymerase subunits, forms the DNA-binding domain of the polymerase, a groove in which the DNA template is transcribed into RNA.
Host Mouse
Immunogen Synthetic peptide (TSPSYSPTSPSYSPTSPSYSP) coupled to ovalbumin.
Subclass IgG1 kappa
Notes Available in 100ul unit as ascites.
Research Area Epigenetics & Nuclear Signalling

References: 1 entry

Bonnet et al. 1999. Nucleic Acids Res. 27(22):4399-404. PMID: 10536148.


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References: 1 entry

Bonnet et al. 1999. Nucleic Acids Res. 27(22):4399-404. PMID: 10536148.


Add a reference

References: 1 entry

Bonnet et al. 1999. Nucleic Acids Res. 27(22):4399-404. PMID: 10536148.


Add a reference


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