Anti-ACTR2 [149/1]
Invented by Prof Roy Bicknell from University Of Birmingham
Invented at University of Oxford
- Datasheet
- References (6)
- Inventor Info
Info
| Catalogue Number | 151217 |
| Applications | IHC IF IP WB |
| Antigen/Gene or Protein Targets | Activin receptor type 2 (ACTR2) |
| Reactivity | Human |
| Relevance | ACTR2 is a serine/threonine kinase receptor. Activin signal transduction pathways are implicated in diverse developmental and physiological processes. Activin is implicated in control of vascular endothelial growth. |
| Host | Mouse |
| Immunogen | Recombinant fusion protein composed of the intracellular kinase domain of the human type 2 activin receptor fused to gluthathion S-transferase |
| Subclass | IgG1 |
| Myeloma Used | P3/NS1/1-Ag4.1 |
| Recommended Growing Conditions | DMEM + 5% FCS. Thaw into DMEM + 10% FCS and 10% Iscoves and reduce to DMEM + 5% FCS |
| Strain | Balb/c |
| Research Area | Cardiovascular, Cell Signaling & Signal Transduction, Cell Structure and Motility, Developmental Biology |
References: 6 entries
Zhu et al. 2007. J Neurosci. 27(50):13770-80. PMID: 18077689.
IF WB
Activin acutely sensitizes dorsal root ganglion neurons and induces hyperalgesia via PKC-mediated potentiation of transient receptor potential vanilloid I.
Europe PMC ID: 18077689
McCarthy et al. 1994. Hybridoma. 13(3):199-203. PMID: 7927363.
Monoclonal antibodies that recognize the type-2 activin receptor, ACTR2.
Europe PMC ID: 7927363
McCarthy et al. 1994. J Biol Chem. 269(6):3909-12. PMID: 8307945.
Activin-A binds to a heterotrimeric receptor complex on the vascular endothelial cell surface. Evidence for a type 3 activin receptor.
Europe PMC ID: 8307945
Add a reference
References: 6 entries
Zhu et al. 2007. J Neurosci. 27(50):13770-80. PMID: 18077689.
IF WB
Activin acutely sensitizes dorsal root ganglion neurons and induces hyperalgesia via PKC-mediated potentiation of transient receptor potential vanilloid I.
McCarthy et al. 1994. Hybridoma. 13(3):199-203. PMID: 7927363.
Monoclonal antibodies that recognize the type-2 activin receptor, ACTR2.
McCarthy et al. 1994. J Biol Chem. 269(6):3909-12. PMID: 8307945.
Activin-A binds to a heterotrimeric receptor complex on the vascular endothelial cell surface. Evidence for a type 3 activin receptor.
Add a reference
