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Anti-POLR1B [1POL-2D3]

Info

Applications ELISA IF WB
Antigen/Gene or Protein Targets  RNA Polymerase I (Polypeptide B), POLR1B
Reactivity Human
Relevance DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Second largest core component of RNA polymerase I which synthesizes ribosomal RNA precursors. Proposed to contribute to the polymerase catalytic activity and forms the polymerase active center together with the largest subunit. Pol I is composed of mobile elements and RPA2 is part of the core element with the central large cleft and probably a clamp element that moves to open and close the cleft.
Host Mouse
Immunogen Synthetic peptide: (C)-YGIPREQQKAALQELTRAHVES corresponding to aa 24 to 45 of human Polymerase I (Polypeptide B).
Subclass IgG2a kappa
Notes Available in 100ul unit as ascites.
Research Area Epigenetics & Nuclear Signalling

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