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Anti-MMS19 [3MM-3H10]

Info

Applications ELISA IF WB
Antigen/Gene or Protein Targets  MMS19 
Reactivity Human
Relevance MMS19 may play a role in nucleotide excision repair (NER) and RNA polymerase II (POL II) transcription by interacting with ERCC2/XPD and ERCC3/XPB helicases, both subunits of NER-transcription factor TFIIH. MMS19 may also function as a transcriptional coactivator of estrogen receptor (ER). May be involved in regulation of ER activity by bridging TFIIH with ER or may facilitate TFIIH-mediated phosphorylation of ER in specific promoters and cell types. As part of the mitotic spindle-associated MMXD complex it plays a role in chromosome segregation.
Host Mouse
Immunogen Recombinant protein
Subclass IgG1 kappa
Notes Available in 100ul unit
Research Area Adhesion, Cancer, Cardiovascular, Cell Structure and Motility

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