Anti-MMS19 [3MM-3H10]
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Info
| Applications | ELISA IF WB |
| Antigen/Gene or Protein Targets | MMS19 |
| Reactivity | Human |
| Relevance | MMS19 may play a role in nucleotide excision repair (NER) and RNA polymerase II (POL II) transcription by interacting with ERCC2/XPD and ERCC3/XPB helicases, both subunits of NER-transcription factor TFIIH. MMS19 may also function as a transcriptional coactivator of estrogen receptor (ER). May be involved in regulation of ER activity by bridging TFIIH with ER or may facilitate TFIIH-mediated phosphorylation of ER in specific promoters and cell types. As part of the mitotic spindle-associated MMXD complex it plays a role in chromosome segregation. |
| Host | Mouse |
| Immunogen | Recombinant protein |
| Subclass | IgG1 kappa |
| Notes | Available in 100ul unit |
| Research Area | Adhesion, Cancer, Cardiovascular, Cell Structure and Motility |
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