Anti-MMP14 [4MMP-2A7]
- Datasheet
- References (2)
- Inventor Info
Info
| Applications | ELISA IHC IF WB |
| Antigen/Gene or Protein Targets | MMP14 (matrix metalloproteinase) |
| Reactivity | Human |
| Relevance | MMP14 or MT1MMP is an endopeptidase that degrades various components of the extracellular matrix, such as collagen. MMP14 activates progelatinase A (pro‐MMP2) and is essential for pericellular collagenolysis and modeling of skeletal and extraskeletal connective tissues during development. MMP14 is present in many human invasive carcinoma and is almost exclusively located to the stromal cells. |
| Host | Mouse |
| Immunogen | Recomb prot |
| Subclass | IgG1 kappa |
| Notes | Available in 100ul unit |
| Research Area | Adhesion, Cancer, Cardiovascular, Epigenetics & Nuclear Signalling |
References: 2 entries
Chenard et al. 1999. Int J Cancer. 82(2):208-12. PMID: 10389754.
Presence of high levels of MT1-MMP protein in fibroblastic cells of human invasive carcinomas.
Europe PMC ID: 10389754
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References: 2 entries
Chenard et al. 1999. Int J Cancer. 82(2):208-12. PMID: 10389754.
Presence of high levels of MT1-MMP protein in fibroblastic cells of human invasive carcinomas.
Add a reference
