Anti-Acetyl Histone H4 (K8 or K12) [3HH4-2E3]
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Info
| Applications | ELISA WB |
| Antigen/Gene or Protein Targets | Histone H4 acetylated (K8 or K12) |
| Reactivity | Human and Mouse |
| Relevance | Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. |
| Host | Mouse |
| Immunogen | MSGRG(acetyl-K)GG(acetyl-K)GLG(acetyl-K)GGA(acetyl-K)RHRKVLR-(C) |
| Subclass | IgG1 kappa |
| Notes | Available in 100ul unit as ascites. |
| Research Area | DNA Damage and Repair, Epigenetics & Nuclear Signalling |
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