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Anti-Histone H2B  [5HH2-2A8]

Info

Applications ELISA IF WB
Antigen/Gene or Protein Targets  Histone H2b 
Reactivity N/A
Relevance The monoclonal anti‐ Histone H2b, clone 5HH2‐2A8, has been validated for ELISA, Western Blot and Immunoprecipitation. Histone H2B is one of the 5 main histone proteins involved in the structure of chromatin in eukaryotic cells. Featuring a main globular domain and long N-terminal and C-terminal tails, H2B is involved with the structure of the nucleosomes. It plays an important role in the biology of the nucleus where it is involved in the packaging and maintaining of chromosomes,regulation of transcription, and replication and repair of DNA. Histone H2B helps regulate chromatin structure and function through post-translational modifications and specialized histone variants.
Host Mouse
Immunogen VSEGTKAVTKYTSSK(C) corresponding to aa 111‐125 of human H2b. This sequence is conserved in a wide range of species.
Subclass IgG1 kappa
Notes Available in 100ul unit

Recommended dilutions: 1/500‐1/5000
Research Area Epigenetics & Nuclear Signalling

References: 1 entry

Bonnet et al. 2010. EMBO Rep. 11(8):612-8. PMID: 20634802.


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References: 1 entry

Bonnet et al. 2010. EMBO Rep. 11(8):612-8. PMID: 20634802.


Add a reference

References: 1 entry

Bonnet et al. 2010. EMBO Rep. 11(8):612-8. PMID: 20634802.


Add a reference


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