Anti-ATF7 [1AT 2F10]

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Applications	ELISA IF IP WB
Antigen/Gene or Protein Targets	ATF7 Transcription Factor
Reactivity	Human
Relevance	The monoclonal anti-ATF7 antibody, clone 1AT-2F10, has been validated for ELISA, Western Blot, Immunofluorescence, Immunoprecipitation and gel supershift applications. ATF-7 is a cyclic AMP-dependent transcription factor that in humans is encoded by the ATF7 gene. The ATF7 homolog Drosophila ATF2 (dATF2) contributes to heterochromatin formation and mouse ATF7 also contributes to the formation of heterochromatin on the gene encoding serotonin receptor 5b (Htr5b). ATF7 mediates epigenetic changes induced by LPS in human and mouse macrophages and these changes are maintained for long periods.
Host	Mouse
Immunogen	Recombinant protein (1-494)
Subclass	IgG1 kappa
Notes	Available in 100ul unit as ascites. Epitope localized between aa 257 and 398. Recommended dilutions: 1/500-1/5000
Research Area	Epigenetics & Nuclear Signalling

Hamard et al. 2005. Oncogene. 24(21):3472-83. PMID: 15735663.

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Hamard et al. 2005. Oncogene. 24(21):3472-83. PMID: 15735663.

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Hamard et al. 2005. Oncogene. 24(21):3472-83. PMID: 15735663.

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Add a reference

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