Anti-uncarboxylated osteocalcin (ucOC) [Fab-16] recombinant antibody
Invented by Kaisa Ivaska-Papaioannou , Urpo Lamminmäki
Invented at University Of Turku
- References (1)
- Inventor Info
|Antigen/Gene or Protein Targets||osteocalcin - partially carboxylated with Glu at position 17|
|Synonyms||Uncarboxylated osteocalcin, uc-Osteocalcin, uc-OC, bone gamma-carboxyglutamic acid-containing protein, BGLAP|
|Relevance||Recombinant antibody binding to partially carboxylated osteocalcin with Glu at position 17|
|Immunogen||Human full-length ucOC peptide (1–49, Glu at positions 17, 21 and 24; C23–C29 bridge)|
Adapted from Arponen et al Calcified Tissue International volume 107, pages 529–542(2020).
These ucOC-specific recombinant antibodies were selected from an antibody library by phage display. Four candidates were characterized - all linked in the above "Related" tab.
|Research Area||Diabetes, Metabolism, Other|
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