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Catalogue Number
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157716 |
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Antigen/Gene or Protein Targets
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Prostate Cancer
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Parental Line
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PF179T
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Host
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Human
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Tissue
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Fibroblast
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Disease Keywords
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Prostate Cancer
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Model
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Tumour line
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Relevance
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Fibroblasts located adjacent to the tumour (cancer-associated fibroblasts (CAFs)) that constitute a large proportion of the cancer-associated stroma facilitate the transformation process.This cell line can be used to help to understand the biological behaviour of CAFs in cells isolated from a human prostate tumour.
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Production Details
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Primary human prostate fibroblasts (PFs) (designated PF179; 179, patient number) were isolated from a prostatectomy specimen, marginal and distal to the prostate tumor. (PMID: 18842679).
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Conditional
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No
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Research Area
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Cancer
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Growth/Phenotype Keywords
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Fibroblast
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Recommended Growing Conditions
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Recommend growth in minimum essential medium supplemented with 10% fetal calf serum, 2 mM l-glutamine, 1 mM sodium pyruvate and antibiotics. Publication PMID: 18842679
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Cellosaurus ID
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CVCL_JL59
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