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hTERT PF179T CAF cell line

Info

Catalogue Number 157716
Antigen/Gene or Protein Targets Prostate Cancer
Parental Line PF179T
Host Human
Tissue Fibroblast
Disease Keywords Prostate Cancer
Model Tumour line
Relevance Fibroblasts located adjacent to the tumour (cancer-associated fibroblasts (CAFs)) that constitute a large proportion of the cancer-associated stroma facilitate the transformation process.This cell line can be used to help to understand the biological behaviour of CAFs in cells isolated from a human prostate tumour.
Production Details Primary human prostate fibroblasts (PFs) (designated PF179; 179, patient number) were isolated from a prostatectomy specimen, marginal and distal to the prostate tumor. (PMID: 18842679).
Conditional No
Research Area Cancer
Growth/Phenotype Keywords Fibtroblast
Recommended Growing Conditions Recommend growth in minimum essential medium supplemented with 10% fetal calf serum, 2 mM l-glutamine, 1 mM sodium pyruvate and antibiotics. Publication PMID: 18842679
Cellosaurus ID CVCL_JL59

References

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References: 1 entry

Madar et al. 2009. Carcinogenesis. 30(1):20-7. PMID: 18842679.


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References: 1 entry

Madar et al. 2009. Carcinogenesis. 30(1):20-7. PMID: 18842679.


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