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Anti-SOX9, Polyclonal

Info

Catalogue Number 153658
Applications ChIP IF WB
Antigen/Gene or Protein Targets SOX9
Synonyms SOX9, CMPD1, CMD1, SRA1
Reactivity Chicken, Human, Mouse and Rabbit
Relevance The Sox genes are a family of genes related to the mammalian sex determining gene ex-determining region Y protein (SRY). SOX genes genes similarly contain sequences that encode for the HMG-box domain, which is responsible for the sequence-specific DNA binding activity. Sox genes encode putative transcriptional regulators which have been implicated in the process of development and cell fate. At present 30 Sox genes have been identified and members of the family are conserved during evolution. Transcription factor SOX9 recognizes the sequence "CCTTGAG" as do other members of the high mobility group-box class DNA-binding proteins.
Host Rabbit
Method of Purification Rabbit Serum, IgG purified by ammonium sulphate precipitation and chromatoraphy.
Notes Epitope: VPSIPQTHSPQHWEQPVYTQLRP
Research Area Cell Signaling & Signal Transduction

References: 14 entries

Zwolanek et al. 2017. JCI Insight. 2(20):. PMID: 29046476.

Tracking mesenchymal stem cell contributions to regeneration in an immunocompetent cartilage regeneration model.

Europe PMC ID: 29046476

Qi et al. 2017. Nat Commun. 8:13824. PMID: 28059064.

BMP restricts stemness of intestinal Lgr5+ stem cells by directly suppressing their signature genes.

Europe PMC ID: 28059064

Kim et al. 2017. J Clin Invest. 127(1):137-152. PMID: 27869648.

Hippo signaling interactions with Wnt/β-catenin and Notch signaling repress liver tumorigenesis.

Europe PMC ID: 27869648

Temporal Analysis of Gene Expression in the Murine Schwann Cell Lineage and the Acutely Injured Postnatal Nerve.

Europe PMC ID: 27058953

Balakrishnan et al. 2016. PLoS One. 11(4):e0153256. PMID: 27058953.

Krah et al. 2015. Elife. 4:. PMID: 26151762.

The acinar differentiation determinant PTF1A inhibits initiation of pancreatic ductal adenocarcinoma.

Europe PMC ID: 26151762

Xu et al. 2014. EMBO J. 33(19):2157-70. PMID: 25107471.

Dynamics of genomic H3K27me3 domains and role of EZH2 during pancreatic endocrine specification.

Europe PMC ID: 25107471

Morais da Silva et al. 1996. Nat Genet. 14(1):62-8. PMID: 8782821.

Sox9 expression during gonadal development implies a conserved role for the gene in testis differentiation in mammals and birds.

Europe PMC ID: 8782821


Add a reference

References: 14 entries

Zwolanek et al. 2017. JCI Insight. 2(20):. PMID: 29046476.

Tracking mesenchymal stem cell contributions to regeneration in an immunocompetent cartilage regeneration model.

Europe PMC ID: 29046476

Qi et al. 2017. Nat Commun. 8:13824. PMID: 28059064.

BMP restricts stemness of intestinal Lgr5+ stem cells by directly suppressing their signature genes.

Europe PMC ID: 28059064

Kim et al. 2017. J Clin Invest. 127(1):137-152. PMID: 27869648.

Hippo signaling interactions with Wnt/β-catenin and Notch signaling repress liver tumorigenesis.

Europe PMC ID: 27869648

Temporal Analysis of Gene Expression in the Murine Schwann Cell Lineage and the Acutely Injured Postnatal Nerve.

Europe PMC ID: 27058953

Balakrishnan et al. 2016. PLoS One. 11(4):e0153256. PMID: 27058953.

Krah et al. 2015. Elife. 4:. PMID: 26151762.

The acinar differentiation determinant PTF1A inhibits initiation of pancreatic ductal adenocarcinoma.

Europe PMC ID: 26151762

Xu et al. 2014. EMBO J. 33(19):2157-70. PMID: 25107471.

Dynamics of genomic H3K27me3 domains and role of EZH2 during pancreatic endocrine specification.

Europe PMC ID: 25107471

Morais da Silva et al. 1996. Nat Genet. 14(1):62-8. PMID: 8782821.

Sox9 expression during gonadal development implies a conserved role for the gene in testis differentiation in mammals and birds.

Europe PMC ID: 8782821


Add a reference

References: 14 entries

Zwolanek et al. 2017. JCI Insight. 2(20):. PMID: 29046476.

Tracking mesenchymal stem cell contributions to regeneration in an immunocompetent cartilage regeneration model.

Qi et al. 2017. Nat Commun. 8:13824. PMID: 28059064.

BMP restricts stemness of intestinal Lgr5+ stem cells by directly suppressing their signature genes.

Kim et al. 2017. J Clin Invest. 127(1):137-152. PMID: 27869648.

Hippo signaling interactions with Wnt/β-catenin and Notch signaling repress liver tumorigenesis.

Temporal Analysis of Gene Expression in the Murine Schwann Cell Lineage and the Acutely Injured Postnatal Nerve.

Balakrishnan et al. 2016. PLoS One. 11(4):e0153256. PMID: 27058953.

Krah et al. 2015. Elife. 4:. PMID: 26151762.

The acinar differentiation determinant PTF1A inhibits initiation of pancreatic ductal adenocarcinoma.

Xu et al. 2014. EMBO J. 33(19):2157-70. PMID: 25107471.

Dynamics of genomic H3K27me3 domains and role of EZH2 during pancreatic endocrine specification.

Morais da Silva et al. 1996. Nat Genet. 14(1):62-8. PMID: 8782821.

Sox9 expression during gonadal development implies a conserved role for the gene in testis differentiation in mammals and birds.


Add a reference


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