Anti-SOX9, Polyclonal
Invented at Hudson Institute Of Medical Research
- Datasheet
- References (14)
- Inventor Info
Info
| Catalogue Number | 153658 |
| Applications | ChIP IF WB |
| Antigen/Gene or Protein Targets | SOX9 |
| Synonyms | SOX9, CMPD1, CMD1, SRA1 |
| Reactivity | Chicken, Human, Mouse and Rabbit |
| Relevance | The Sox genes are a family of genes related to the mammalian sex determining gene ex-determining region Y protein (SRY). SOX genes genes similarly contain sequences that encode for the HMG-box domain, which is responsible for the sequence-specific DNA binding activity. Sox genes encode putative transcriptional regulators which have been implicated in the process of development and cell fate. At present 30 Sox genes have been identified and members of the family are conserved during evolution. Transcription factor SOX9 recognizes the sequence "CCTTGAG" as do other members of the high mobility group-box class DNA-binding proteins. |
| Host | Rabbit |
| Method of Purification | Rabbit Serum, IgG purified by ammonium sulphate precipitation and chromatoraphy. |
| Notes | Epitope: VPSIPQTHSPQHWEQPVYTQLRP |
| Research Area | Cell Signaling & Signal Transduction |
References: 14 entries
Zwolanek et al. 2017. JCI Insight. 2(20):. PMID: 29046476.
Tracking mesenchymal stem cell contributions to regeneration in an immunocompetent cartilage regeneration model.
Europe PMC ID: 29046476
Qi et al. 2017. Nat Commun. 8:13824. PMID: 28059064.
BMP restricts stemness of intestinal Lgr5+ stem cells by directly suppressing their signature genes.
Europe PMC ID: 28059064
Kim et al. 2017. J Clin Invest. 127(1):137-152. PMID: 27869648.
Hippo signaling interactions with Wnt/β-catenin and Notch signaling repress liver tumorigenesis.
Europe PMC ID: 27869648
Temporal Analysis of Gene Expression in the Murine Schwann Cell Lineage and the Acutely Injured Postnatal Nerve.
Europe PMC ID: 27058953
Balakrishnan et al. 2016. PLoS One. 11(4):e0153256. PMID: 27058953.
Krah et al. 2015. Elife. 4:. PMID: 26151762.
The acinar differentiation determinant PTF1A inhibits initiation of pancreatic ductal adenocarcinoma.
Europe PMC ID: 26151762
Xu et al. 2014. EMBO J. 33(19):2157-70. PMID: 25107471.
Dynamics of genomic H3K27me3 domains and role of EZH2 during pancreatic endocrine specification.
Europe PMC ID: 25107471
Morais da Silva et al. 1996. Nat Genet. 14(1):62-8. PMID: 8782821.
Sox9 expression during gonadal development implies a conserved role for the gene in testis differentiation in mammals and birds.
Europe PMC ID: 8782821
Add a reference
References: 14 entries
Zwolanek et al. 2017. JCI Insight. 2(20):. PMID: 29046476.
Tracking mesenchymal stem cell contributions to regeneration in an immunocompetent cartilage regeneration model.
Qi et al. 2017. Nat Commun. 8:13824. PMID: 28059064.
BMP restricts stemness of intestinal Lgr5+ stem cells by directly suppressing their signature genes.
Kim et al. 2017. J Clin Invest. 127(1):137-152. PMID: 27869648.
Hippo signaling interactions with Wnt/β-catenin and Notch signaling repress liver tumorigenesis.
Temporal Analysis of Gene Expression in the Murine Schwann Cell Lineage and the Acutely Injured Postnatal Nerve.
Balakrishnan et al. 2016. PLoS One. 11(4):e0153256. PMID: 27058953.
Krah et al. 2015. Elife. 4:. PMID: 26151762.
The acinar differentiation determinant PTF1A inhibits initiation of pancreatic ductal adenocarcinoma.
Xu et al. 2014. EMBO J. 33(19):2157-70. PMID: 25107471.
Dynamics of genomic H3K27me3 domains and role of EZH2 during pancreatic endocrine specification.
Morais da Silva et al. 1996. Nat Genet. 14(1):62-8. PMID: 8782821.
Sox9 expression during gonadal development implies a conserved role for the gene in testis differentiation in mammals and birds.
Add a reference
