Cancer Research Technology
Log in Register
Menu

Anti-Keratin 7 & 8 [LDS65]

Invented by Prof Jenny Southgate at University Of York

Info

Catalogue Number 151742
Applications IHC
Antigen/Gene or Protein Targets Keratin 7 and Keratin 8
Reactivity Human
Relevance Keratins are a family of intermediate filament proteins that assemble into filaments through forming heterodimers of one type I keratin (keratins 9 to 23) and one type II keratin (keratins 1 to 8). Keratins

demonstrate tissue and differentiation specific expression profiles. Keratins 7 and 8 are two closely related type II keratins characteristic of simple epithelia. Keratin 7 is less widespread than keratin 8 and is expressed in sebaceous and sweat glands and some cells of the inner hair root sheath. Keratin 7 is often co-expressed with keratin 19. LdS 65 is useful for studies of epithelial cells and tumour origin.
Host Mouse
Immunogen Cytoskeletons of the human urothelial RT4 cell line
Subclass Not Known
Recommended Growing Conditions DMEM + 5% FCS
Research Area Cell Signaling & Signal Transduction

References: 4 entries

Southgate et al. 1987. Lab Invest. 56(2):211-23. PMID: 2433501.

Primary culture of human oral epithelial cells. Growth requirements and expression of differentiated characteristics.

Europe PMC ID: 2433501

Trejdosiewicz et al. 1986. Exp Cell Res. 164(2):388-98. PMID: 2423348.

Phenotypic analysis of cultured melanoma cells. Expression of cytokeratin-type intermediate filaments by the M5 human melanoma cell line.

Europe PMC ID: 2423348


Add a reference

References: 4 entries

Southgate et al. 1987. Lab Invest. 56(2):211-23. PMID: 2433501.

Primary culture of human oral epithelial cells. Growth requirements and expression of differentiated characteristics.

Europe PMC ID: 2433501

Trejdosiewicz et al. 1986. Exp Cell Res. 164(2):388-98. PMID: 2423348.

Phenotypic analysis of cultured melanoma cells. Expression of cytokeratin-type intermediate filaments by the M5 human melanoma cell line.

Europe PMC ID: 2423348


Add a reference

References: 4 entries

Southgate et al. 1987. Lab Invest. 56(2):211-23. PMID: 2433501.

Primary culture of human oral epithelial cells. Growth requirements and expression of differentiated characteristics.

Trejdosiewicz et al. 1986. Exp Cell Res. 164(2):388-98. PMID: 2423348.

Phenotypic analysis of cultured melanoma cells. Expression of cytokeratin-type intermediate filaments by the M5 human melanoma cell line.


Add a reference


This reagent does not have any reviews at the moment.