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Anti-Keratin 7 & 8 [LDS65]

Invented by Prof Jenny Southgate at University Of York

Info

Catalogue Number 151742
Applications IHC
Antigen/Gene or Protein Targets Keratin 7 and Keratin 8
Reactivity Human
Relevance Keratins are a family of intermediate filament proteins that assemble into filaments through forming heterodimers of one type I keratin (keratins 9 to 23) and one type II keratin (keratins 1 to 8). Keratins

demonstrate tissue and differentiation specific expression profiles. Keratins 7 and 8 are two closely related type II keratins characteristic of simple epithelia. Keratin 7 is less widespread than keratin 8 and is expressed in sebaceous and sweat glands and some cells of the inner hair root sheath. Keratin 7 is often co-expressed with keratin 19. LdS 65 is useful for studies of epithelial cells and tumour origin.
Host Mouse
Immunogen Cytoskeletons of the human urothelial RT4 cell line
Subclass Not Known
Recommended Growing Conditions DMEM + 5% FCS
Research Area Cell Signaling & Signal Transduction

References: 2 entries

Southgate et al. 1987. Lab Invest. 56(2):211-23. PMID: 2433501.

Trejdosiewicz et al. 1986. Exp Cell Res. 164(2):388-98. PMID: 2423348.


Add a reference

References: 2 entries

Southgate et al. 1987. Lab Invest. 56(2):211-23. PMID: 2433501.

Trejdosiewicz et al. 1986. Exp Cell Res. 164(2):388-98. PMID: 2423348.


Add a reference

References: 2 entries

Southgate et al. 1987. Lab Invest. 56(2):211-23. PMID: 2433501.

Trejdosiewicz et al. 1986. Exp Cell Res. 164(2):388-98. PMID: 2423348.


Add a reference


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