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Anti-FOXC1, Polyclonal [FOXC1]

Info

Applications ELISA IF WB
Antigen/Gene or Protein Targets FOXC1
Reactivity Human and Mouse
Relevance Binding of FREAC­3 and FREAC­4 to their cognate sites results in bending of the DNA at an angle of 80­90 degrees. This gene belongs to the forkhead family of transcription factors which is characterized by a distinct DNA­binding forkhead domain.  The specific function of this gene has not yet been determined; however, it has been shown to play a role in the regulation of embryonic and ocular development. Mutations in this gene cause various glaucoma phenotypes including primary congenital glaucoma, autosomal dominant iridogoniodysgenesis anomaly, and Axenfeld­Rieger anomaly [provided by RefSeq].
Host Rabbit
Immunogen 3 synthetic peptides (human) conjugated to KLH
Formulation 0.5 X PBS, containing a final concentration of 50% Glycerol, 0.1% BSA and 0.01% Thimerosal.
Method of Purification Immunogen affinity purification
Molecular Weight (kDa) 56.8
Research Area Developmental Biology, Epigenetics & Nuclear Signalling

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