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Anti-NR1H4, Polyclonal [NR1H4]

Info

Applications ELISA IF WB
Antigen/Gene or Protein Targets NR1H4
Reactivity Human and Mouse
Relevance Receptor for bile acids such as chenodeoxycholic acid, lithocholic acid and deoxycholic acid. Represses the transcription of the cholesterol 7­alpha­hydroxylase gene (CYP7A1) and activates the intestinal bile acid­binding protein (IBABP). Activates the transcription of bile salt export pump ABCB11 by directly recruiting histone methyltransferase CARM1 within its gene locus.
Host Rabbit
Immunogen 3 synthetic peptides (human) conjugated to KLH
Formulation 0.5 X PBS, containing a final concentration of 50% Glycerol, 0.1% BSA and 0.01% Thimerosal.
Method of Purification Immunogen affinity purification
Molecular Weight (kDa) 55.9 [Isoform1]
55.5 [Isoform2]
54.9 [Isoform3]
54.4 [Isoform4]
Research Area Cancer, Cell Signaling & Signal Transduction, Epigenetics & Nuclear Signalling, Metabolism

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