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Anti-USP3 [AE9-12-1]

Info

Applications IP WB
Antigen/Gene or Protein Targets Ubiquitin Speciļ¬c Protease 3
Synonyms Deubiquitinating enzyme 3, EC 3.1.2.15, SIH003, Ubiquitin carboxyl-terminal hydrolase 3, Ubiquitin specific peptidase 3, Ubiquitin specific processing protease 3, Ubiquitin Specific Protease 3, Ubiquitin thioesterase 3, Ubiquitin thiolesterase 3, Ubiquitin-specific-processing protease 3, UBP, UBP3_HUMAN, Usp3
Reactivity Human and Mouse
Relevance Hydrolase that deubiquitinates monoubiquitinated target proteins such as histone H2A and H2B. Required for proper progression through S phase and subsequent mitotic entry. May regulate the DNA damage response (DDR) checkpoint through deubiquitination of H2A at DNA damage sites. Associates with the chromatin.
Host Mouse
Myeloma Used Sp2/0
Research Area Cancer, Cell Signaling & Signal Transduction, DNA Damage and Repair, Epigenetics & Nuclear Signalling, Metabolism, Protein Degradation

References

There are 2 reference entries for this reagent.

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References: 2 entries

Nicassio et al. 2007. Curr Biol. 17(22):1972-7. PMID: 17980597.

Human USP3 is a chromatin modifier required for S phase progression and genome stability.

Europe PMC ID: 17980597


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References: 2 entries

Nicassio et al. 2007. Curr Biol. 17(22):1972-7. PMID: 17980597.

Human USP3 is a chromatin modifier required for S phase progression and genome stability.


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