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Anti-WASF2 [ZZ36-12]

Info

Applications IF IP WB
Antigen/Gene or Protein Targets Wiskott Aldrich syndrome protein family member 2
Synonyms DICTYOSTELIUM, dJ393P12.2, IMD2, Protein WAVE-2, Putative Wiskott Aldrich syndrome protein family member 4, SCAR 2, SCAR, SCAR2, Suppressor of cyclic-AMP receptor (WASP family), Verprolin homology domain-containing protein 2,
Reactivity Human and Mouse
Relevance Downstream effector molecule involved in the transmission of signals from tyrosine kinase receptors and small GTPases to the actin cytoskeleton. Promotes formation of actin filaments. Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex.
Host Mouse
Subclass IgG1 kappa
Myeloma Used Sp2/0
Research Area Cancer, Cell Signaling & Signal Transduction

References

There are 2 reference entries for this reagent.

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References: 2 entries

Innocenti et al. 2004. Nat Cell Biol. 6(4):319-27. PMID: 15048123.

Abi1 is essential for the formation and activation of a WAVE2 signalling complex.

Europe PMC ID: 15048123


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References: 2 entries

Innocenti et al. 2004. Nat Cell Biol. 6(4):319-27. PMID: 15048123.

Abi1 is essential for the formation and activation of a WAVE2 signalling complex.


Add a reference

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