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Info
Applications | ELISA IF WB |
Antigen/Gene or Protein Targets | SNAI1 |
Reactivity | Human and Mouse |
Relevance | Seems to be involved in embryonic mesoderm formation. Binds to 3 Eboxes of the Ecadherin gene promoter and represses its transcription. The drosophila embryonic protein snail is a zinc finger transcriptional repressor which downregulates the expression of ectodermal genes within the mesoderm. The nuclear protein encoded by this gene is structurally similar to the Drosophila snail protein, and is also thought to be critical for mesoderm formation in the developing embryo. At least two variants of a similar processed pseudogene have been found on chromosome 2. [provided by RefSeq] |
Host | Rabbit |
Immunogen | 3 synthetic peptides (human) conjugated to KLH |
Molecular Weight (kDa) | 29.083 |
Research Area | Cancer, Cardiovascular, Epigenetics & Nuclear Signalling |
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