|
Catalogue Number
|
154760 |
|
Applications
|
EM
ELISA
FACS
IHC
IF
IP
WB
|
|
Antigen/Gene or Protein Targets
|
CD227
|
|
Synonyms
|
Mucin 1, Cell Surface Associated
|
|
Reactivity
|
Human
|
|
Relevance
|
MUC1 is a glycoprotein with extensive O-linked glycosylation of its extracellular domain. Mucins line the apical surface of epithelial cells in the lungs, stomach, intestines, eyes and several other organs. Mucins protect the body from infection by pathogen binding to oligosaccharides in the extracellular domain, preventing the pathogen from reaching the cell surface. Overexpression of MUC1 is often associated with colon, breast, ovarian, lung and pancreatic cancers
|
|
Host
|
Mouse
|
|
Immunogen
|
Milkfat globule membranes
|
|
Subclass
|
IgG1
|
|
Molecular Weight (kDa)
|
120
|
|
Recommended Growing Conditions
|
DMEM + 10% FBS ultra low IgG, 37⁰C 5% CO2
|
|
Research Area
|
Cancer, Cell Signaling & Signal Transduction
|
