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Anti-cMyc, Recombinant [9E10]

Info

Catalogue Number 152580
Applications WB
Antigen/Gene or Protein Targets c Myc epitope tag
Reactivity Human
Relevance c-Myc is a very strong proto-oncogene and it is very often found to be upregulated in many types of cancers. Through its role as a transcription factor, c-Myc alters the expression of hundreds of target genes, many of which are themselves oncogenes or tumor suppressors. 9E10 recognises recombinant proteins incorporating a c-Myc epitope tag and detects human c-Myc protein as well as a peptide in random coil configuration not as a helix.
Host Mouse
Immunogen Synthetic peptide (AEEQKLISEEDLLRKRREQLKHKLEQLRNSCA - 32 aa) corresponding to 408-439 of Human c-Myc conjugated to KLH.
Subclass IgG1 kappa
Formulation PBS only
Concentration 1mg/ml
Research Area Cancer, Cell Cycle, Epigenetics & Nuclear Signalling, Stem Cell Biology
Notes Recombinant monoclonal antibody produced from the original monoclonal. Manufactured using Absolute Antibody’s Recombinant Platform with variable regions (i.e. specificity) from the hybridoma.

Epitope QKLISEEDL in its random, free peptide conformation.

References: 2 entries

Original hybridoma first published in: Evan et al. 1985. Mol Cell Biol. 5(12):3610-6. PMID: 3915782.

Isolation of monoclonal antibodies specific for human c-myc proto-oncogene product.

Europe PMC ID: 3915782


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References: 2 entries

Original hybridoma first published in: Evan et al. 1985. Mol Cell Biol. 5(12):3610-6. PMID: 3915782.

Isolation of monoclonal antibodies specific for human c-myc proto-oncogene product.

Europe PMC ID: 3915782


Add a reference

References: 2 entries

Original hybridoma first published in: Evan et al. 1985. Mol Cell Biol. 5(12):3610-6. PMID: 3915782.

Isolation of monoclonal antibodies specific for human c-myc proto-oncogene product.


Add a reference


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