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Anti-cMyc [9E10]

Info

Catalogue Number 151067
Applications ChIP ELISA IHC IP WB
Antigen/Gene or Protein Targets c Myc epitope tag
Reactivity Human
Relevance c-Myc is a very strong proto-oncogene and it is very often found to be upregulated in many types of cancers. Through its role as a transcription factor, c-Myc alters the expression of hundreds of target genes, many of which are themselves oncogenes or tumor suppressors. 9E10 recognises recombinant proteins incorporating a c-Myc epitope tag and detects human c-Myc protein as well as a peptide in random coil configuration not as a helix.
Host Mouse
Immunogen Synthetic peptide (AEEQKLISEEDLLRKRREQLKHKLEQLRNSCA - 32 aa) corresponding to 408-439 of Human c-Myc conjugated to KLH.
Subclass IgG1 kappa
Myeloma Used Sp2/0-Ag14
Recommended Growing Conditions DMEM + 5% FCS
Strain Balb/c
Research Area Cancer, Cell Cycle, Epigenetics & Nuclear Signalling, Stem Cell Biology

References: 8 entries

Mateos-Gomez et al. 2015. Nature. 518(7538):254-7. PMID: 25642960.

WB

Zhang et al. 2014. Genes Dev. 28(8):829-34. PMID: 24736842.

ChIP

Zhou et al. 2012. J Cell Biol. 196(2):203-11. PMID: 22270916.

IP WB

Mendes et al. 2010. J Biol Chem. 285(50):39117-26. PMID: 20937822.

IP WB

Royds et al. 1992. J Pathol. 166(3):225-33. PMID: 1381423.

IHC

Spandidos et al. 1987. Anticancer Res. 7(6):1299-304. PMID: 3327455.

IHC

Kari et al. 1986. J Virol. 60(2):345-52. PMID: 3021969.

IP

Evan et al. 1985. Mol Cell Biol. 5(12):3610-6. PMID: 3915782.

WB


Add a reference

References: 8 entries

Mateos-Gomez et al. 2015. Nature. 518(7538):254-7. PMID: 25642960.

WB

Zhang et al. 2014. Genes Dev. 28(8):829-34. PMID: 24736842.

ChIP

Zhou et al. 2012. J Cell Biol. 196(2):203-11. PMID: 22270916.

IP WB

Mendes et al. 2010. J Biol Chem. 285(50):39117-26. PMID: 20937822.

IP WB

Royds et al. 1992. J Pathol. 166(3):225-33. PMID: 1381423.

IHC

Spandidos et al. 1987. Anticancer Res. 7(6):1299-304. PMID: 3327455.

IHC

Kari et al. 1986. J Virol. 60(2):345-52. PMID: 3021969.

IP

Evan et al. 1985. Mol Cell Biol. 5(12):3610-6. PMID: 3915782.

WB


Add a reference

References: 8 entries

Mateos-Gomez et al. 2015. Nature. 518(7538):254-7. PMID: 25642960.

WB

Zhang et al. 2014. Genes Dev. 28(8):829-34. PMID: 24736842.

ChIP

Zhou et al. 2012. J Cell Biol. 196(2):203-11. PMID: 22270916.

IP WB

Mendes et al. 2010. J Biol Chem. 285(50):39117-26. PMID: 20937822.

IP WB

Royds et al. 1992. J Pathol. 166(3):225-33. PMID: 1381423.

IHC

Spandidos et al. 1987. Anticancer Res. 7(6):1299-304. PMID: 3327455.

IHC

Kari et al. 1986. J Virol. 60(2):345-52. PMID: 3021969.

IP

Evan et al. 1985. Mol Cell Biol. 5(12):3610-6. PMID: 3915782.

WB


Add a reference


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