Cat. #152580
Anti-cMyc recombinant antibody [9E10]
Cat. #: 152580
Sub-type: Primary antibody
Unit size: 100 ug
Availability: 10-12 weeks
Target: c Myc epitope tag
Class: Recombinant
Application: WB
Reactivity: Human
Host: Mouse
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Inventor: Gerard Evan
Institute: Absolute Antibody ; University of California, San Francisco
Primary Citation: Evan et al. 1985. Mol Cell Biol. 5(12):3610-6. PMID: 3915782.
Tool Details
*FOR RESEARCH USE ONLY
- Name: Anti-cMyc recombinant antibody [9E10]
- Clone: r9E10
- Tool sub type: Primary antibody
- Class: Recombinant
- Conjugation: Unconjugated
- Reactivity: Human
- Host: Mouse
- Application: WB
- Description: Recombinant monoclonal antibody raised against sequence of c-Myc, a proto-oncogene heavily implicated in a variety of (hematopoietic) cancers. The anti-c-Myc antibody is a recombinant version of the monoclonal antibody 9E10, specifically designed to bind to p62 and detect the c-Myc gene product in human cells. It is particularly useful in immunoblots for quantifying c-Myc levels. This recombinant 9E10 antibody can recognize recombinant proteins carrying a c-Myc epitope tag and detect human c-...
- Immunogen: Synthetic peptide (AEEQKLISEEDLLRKRREQLKHKLEQLRNSCA - 32 aa) corresponding to 408-439 of Human c-Myc conjugated to KLH.
- Immunogen uniprot id: P01106
- Isotype: IgG1 kappa
Target Details
- Target: c Myc epitope tag
- Target background: The anti-c-Myc antibody specifically targets the proto-oncogene c-Myc, which is frequently upregulated in cancer. Overexpression of c-Myc is known to contribute to the activation of genes involved in cellular proliferation and has been observed in various cancers, including cervical, colon, breast, lung, stomach, and Burkitt's lymphoma resulting from translocation. The gene product of c-Myc, known as p62, is upregulated in several hematopoietic tumours. Given that c-Myc is believed to regulat...
Applications
- Application: WB
Handling
- Format: Liquid
- Concentration: 1 mg/ml
- Unit size: 100 ug
- Storage buffer: PBS only
- Storage conditions: -15° C to -25° C
- Shipping conditions: Shipping at 4° C
Related Tools
- Related tools: Anti-cMyc [9E10]
References
- Munro and Pelham. 1987. Cell. 13:48(5):899-907. PMID: 3545499.
- Munro and Pelham. 1986 Cell. 18:46(2):291-300. PMID: 3087629.
- Evan et al. 1985. Mol Cell Biol. 5(12):3610-6. PMID: 3915782.
