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Anti-ATRX [39f]

Invented by Helen Turley at University of Oxford

Info

Catalogue Number 151888
Applications IHC IF WB
Antigen/Gene or Protein Targets ATRX
Synonyms RAD54, XNP
Reactivity Human and Mouse
Relevance ATRX is commonly mutated in cancers which maintain their telomores by a telomerase independent pathway - alternative lengthening of telomeres.
Host Mouse
Immunogen Recombinant Protein
Subclass IgG1
Myeloma Used P3/NS1/1-Ag4.1
Recommended Growing Conditions RPMI 1640 + 10% FCS + HAT
Research Area Cancer, Cell Cycle, Epigenetics & Nuclear Signalling

References: 8 entries

Cooper et al. 2016. Nat Commun. 7:13661. PMID: 27892467.

IF

Jarid2 binds mono-ubiquitylated H2A lysine 119 to mediate crosstalk between Polycomb complexes PRC1 and PRC2.

Europe PMC ID: 27892467

Mitson et al. 2011. Hum Mol Genet. 20(13):2603-10. PMID: 21505078.

WB

Functional significance of mutations in the Snf2 domain of ATRX.

Europe PMC ID: 21505078

Lukashchuk et al. 2008. J Virol. 82(24):12543-54. PMID: 18922870.

WB

Human cytomegalovirus protein pp71 displaces the chromatin-associated factor ATRX from nuclear domain 10 at early stages of infection.

Europe PMC ID: 18922870

McDowell et al. 1999. Proc Natl Acad Sci U S A. 96(24):13983-8. PMID: 10570185.

IHC WB

Localization of a putative transcriptional regulator (ATRX) at pericentromeric heterochromatin and the short arms of acrocentric chromosomes.

Europe PMC ID: 10570185


Add a reference

References: 8 entries

Cooper et al. 2016. Nat Commun. 7:13661. PMID: 27892467.

IF

Jarid2 binds mono-ubiquitylated H2A lysine 119 to mediate crosstalk between Polycomb complexes PRC1 and PRC2.

Europe PMC ID: 27892467

Mitson et al. 2011. Hum Mol Genet. 20(13):2603-10. PMID: 21505078.

WB

Functional significance of mutations in the Snf2 domain of ATRX.

Europe PMC ID: 21505078

Lukashchuk et al. 2008. J Virol. 82(24):12543-54. PMID: 18922870.

WB

Human cytomegalovirus protein pp71 displaces the chromatin-associated factor ATRX from nuclear domain 10 at early stages of infection.

Europe PMC ID: 18922870

McDowell et al. 1999. Proc Natl Acad Sci U S A. 96(24):13983-8. PMID: 10570185.

IHC WB

Localization of a putative transcriptional regulator (ATRX) at pericentromeric heterochromatin and the short arms of acrocentric chromosomes.

Europe PMC ID: 10570185


Add a reference

References: 8 entries

Cooper et al. 2016. Nat Commun. 7:13661. PMID: 27892467.

IF

Jarid2 binds mono-ubiquitylated H2A lysine 119 to mediate crosstalk between Polycomb complexes PRC1 and PRC2.

Mitson et al. 2011. Hum Mol Genet. 20(13):2603-10. PMID: 21505078.

WB

Functional significance of mutations in the Snf2 domain of ATRX.

Lukashchuk et al. 2008. J Virol. 82(24):12543-54. PMID: 18922870.

WB

Human cytomegalovirus protein pp71 displaces the chromatin-associated factor ATRX from nuclear domain 10 at early stages of infection.

McDowell et al. 1999. Proc Natl Acad Sci U S A. 96(24):13983-8. PMID: 10570185.

IHC WB

Localization of a putative transcriptional regulator (ATRX) at pericentromeric heterochromatin and the short arms of acrocentric chromosomes.


Add a reference


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