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Anti-Phospho RNA polII (Ser5) [CTD 8A7]


Catalogue Number 151243
Applications ELISA FACS IF WB
Antigen/Gene or Protein Targets RNA Polymerase II (Phosphorylated)
Reactivity Human and Saccharomyces cerevisiae
Relevance RNAPII is an essential component of the RNAP II transcription elongation complex. Recruitment of RNA processing factors to the elongation complex is coordinated by the phosphorylation of Serine-2 and Serine-5 residues within the C-terminal repeat (YSPTSPS) domain of the largest subunit of RNAPII.
Host Mouse
Immunogen Peptide: 10 repeats of synthetic peptide YSPTSPS using chemically sythesized phospho-Ser5.
Subclass IgM
Positive Control S. cerevisiae and HeLa cells
Myeloma Used Sp2/0-Ag14
Recommended Growing Conditions DMEM + 5% FCS
Strain Balb/c
Research Area Epigenetics & Nuclear Signalling

References: 4 entries

Benferhat et al. 2012. J Virol. 86(20):11333-44. PMID: 22896612.


Alm-Kristiansen et al. 2011. Mol Cancer. 10:21. PMID: 21338522.


Aune et al. 2008. Clin Cancer Res. 14(20):6449-55. PMID: 18927284.


Otero et al. 1999. Mol Cell. 3(1):109-18. PMID: 10024884.

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