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HEK293-CEACAM3-Fc cell line

Invented at LeukoCom

Info

Catalogue Number 160689
Antigen/Gene or Protein Targets CEACAM3
Parental Line HEK293
Synonyms Carcinoembryonic antigen-related cell adhesion molecule 3, CD66d, Cluster of Differentiation 66d, CGM1
Host Human
Tissue Kidney
Model Transgenic
Relevance CEACAM-3 is a 31 - 34 kDa member of the CEACAM subfamily of the CEA family of proteins. It is expressed by neutrophils and serves as a microbial receptor for a wide range of microorganisms. Mature human CEACAM-3 is a 218 amino acid (aa) type I transmembrane glycoprotein. Its extracellular domain (aa 35 - 155) shows one V-type Ig-like domain (aa 35 - 142). There are two alternate splice forms of CEACAM-3. One shows a 40 aa substitution for the C-terminal 116 amino acids (aa 137 - 252), while a second shows a 31 aa substitution for the C-terminal 71 amino acids. No definitive rodent CEACAM-3 has been reported
Production Details Overexpression of human CEACAM3-Fc Chimera Protein
Conditional No
Research Area Adhesion, Cancer, Immunology
Growth/Phenotype Keywords Adherent
Recommended Growing Conditions DMEM + 10% FBS

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