HEK293-CEACAM3-Fc cell line
Invented at LeukoCom
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Info
| Catalogue Number | 160689 |
| Antigen/Gene or Protein Targets | CEACAM3 |
| Parental Line | HEK293 |
| Synonyms | Carcinoembryonic antigen-related cell adhesion molecule 3, CD66d, Cluster of Differentiation 66d, CGM1 |
| Host | Human |
| Tissue | Kidney |
| Model | Transgenic |
| Relevance | CEACAM-3 is a 31 - 34 kDa member of the CEACAM subfamily of the CEA family of proteins. It is expressed by neutrophils and serves as a microbial receptor for a wide range of microorganisms. Mature human CEACAM-3 is a 218 amino acid (aa) type I transmembrane glycoprotein. Its extracellular domain (aa 35 - 155) shows one V-type Ig-like domain (aa 35 - 142). There are two alternate splice forms of CEACAM-3. One shows a 40 aa substitution for the C-terminal 116 amino acids (aa 137 - 252), while a second shows a 31 aa substitution for the C-terminal 71 amino acids. No definitive rodent CEACAM-3 has been reported |
| Production Details | Overexpression of human CEACAM3-Fc Chimera Protein |
| Conditional | No |
| Research Area | Adhesion, Cancer, Immunology |
| Growth/Phenotype Keywords | Adherent |
| Recommended Growing Conditions | DMEM + 10% FBS |
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