iCKO-Myrf mouse
Invented at Oregon Health & Science University
- Datasheet
- References (3)
- Inventor Info
Info
| Catalogue Number | 157781 |
| Antigen/Gene or Protein Targets | Myrf (myelin regulatory factor) |
| Disease Keywords | tamoxifen inducible knockout of Myrf in mature oligodendrocytes. |
| Model | Conditional KO |
| Relevance | inducible knockout of Myrf in oligodendrocytes, critical for myelin formation in CNS. |
| Breeding Information | MyrfFl/Fl male + PLP-Cre/MyrfFl/Fl female or PLP-Cre/MyrfFl/Fl male + MyrfFl/Fl female. Provides iCKO-Myrf pups at 50% |
| Conditional | Yes |
| Conditional Description | inducible conditional myelin regulatory factor knockout mouse |
| Growth/Phenotype Keywords | iCKO-Myrf |
| Strain | C57BL/6 |
| Mouse Genetic Background/Cross History | MyrfFl/Fl male + PLP-Cre/MyrfFl/Fl female or PLP-Cre/MyrfFl/Fl male + MyrfFl/Fl female. Provides iCKO-Myrf pups at 50% |
| Research Area | Neurobiology |
References: 3 entries
Koenning et al. 2012. J Neurosci. 32(36):12528-42. PMID: 22956843.
Emery et al. 2009. Cell. 138(1):172-85. PMID: 19596243.
Doerflinger et al. 2003. Genesis. 35(1):63-72. PMID: 12481300.
Add a reference
References: 3 entries
Koenning et al. 2012. J Neurosci. 32(36):12528-42. PMID: 22956843.
Emery et al. 2009. Cell. 138(1):172-85. PMID: 19596243.
Doerflinger et al. 2003. Genesis. 35(1):63-72. PMID: 12481300.
Add a reference
