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iCKO-Myrf mouse
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Catalogue Number 157781
Antigen/Gene or Protein Targets Myrf (myelin regulatory factor)
Disease Keywords tamoxifen inducible knockout of Myrf in mature oligodendrocytes.
Model Conditional KO
Relevance inducible knockout of Myrf in oligodendrocytes, critical for myelin formation in CNS.
Breeding Information MyrfFl/Fl male + PLP-Cre/MyrfFl/Fl female or PLP-Cre/MyrfFl/Fl male + MyrfFl/Fl female. Provides iCKO-Myrf pups at 50%
Conditional Yes
Conditional Description inducible conditional myelin regulatory factor knockout mouse
Growth/Phenotype Keywords iCKO-Myrf
Strain C57BL/6
Mouse Genetic Background/Cross History MyrfFl/Fl male + PLP-Cre/MyrfFl/Fl female or PLP-Cre/MyrfFl/Fl male + MyrfFl/Fl female. Provides iCKO-Myrf pups at 50%
Research Area Neurobiology

References

There are 3 reference entries for this reagent.

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References: 3 entries

Koenning et al. 2012. J Neurosci. 32(36):12528-42. PMID: 22956843.

Emery et al. 2009. Cell. 138(1):172-85. PMID: 19596243.

Doerflinger et al. 2003. Genesis. 35(1):63-72. PMID: 12481300.


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References: 3 entries

Koenning et al. 2012. J Neurosci. 32(36):12528-42. PMID: 22956843.

Emery et al. 2009. Cell. 138(1):172-85. PMID: 19596243.

Doerflinger et al. 2003. Genesis. 35(1):63-72. PMID: 12481300.


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