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PL3 Peptide
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Invented by Prakash Lingasamy, at University of Tartu Tambet Teesalu at University of Tartu

Info

Catalogue Number 157666
Amino Acid Sequence AGRGRLVR
Cellular/Tissue Localisation PL3 is specific to tenascin-C C domain (TNC-C)
Synonyms PL3, Tenascin-C C domain specific peptide
Relevance Tenascin-C C domain (TNC-C) is not present in the extracellular matrix of adult tissues but it is up-regulated in tumours and malignant tissues. It has previously been used as a target for antibody-based therapies. PL3 is a specific peptide which has enhanced affinity to bind to TNC-C so PL3 may be useful as an affinity ligand for delivery of diagnostic compound into solid tumours.
Antigen/Gene or Protein Targets Tenascin-C C domain (TNC-C)
Research Area Cancer, Extracellular Matrix

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Inventor Information

Inventors

Prakash Lingasamy

Prakash Lingasamy

Tambet Teesalu

Tambet Teesalu

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