PL1 peptide
Invented by Tambet Teesalu at University of Tartu
Catalogue Number | 157666 |
Amino Acid Sequence | AGRGRLVR |
Cellular/Tissue Localisation | PL3 is specific to tenascin-C C domain (TNC-C) |
Synonyms | PL3, Tenascin-C C domain specific peptide |
Relevance | Tenascin-C C domain (TNC-C) is not present in the extracellular matrix of adult tissues but it is up-regulated in tumours and malignant tissues. It has previously been used as a target for antibody-based therapies. PL3 is a specific peptide which has enhanced affinity to bind to TNC-C so PL3 may be useful as an affinity ligand for delivery of diagnostic compound into solid tumours. |
Antigen/Gene or Protein Targets | Tenascin-C C domain (TNC-C) |
Research Area | Cancer, Extracellular Matrix |
There are 0 reference entries for this reagent.
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Prakash Lingasamy |
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Tambet Teesalu |