PL3 Peptide
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Invented by Prakash Lingasamy, at University of Tartu Tambet Teesalu at University of Tartu
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Info
| Catalogue Number | 157666 |
| Amino Acid Sequence | AGRGRLVR |
| Cellular/Tissue Localisation | PL3 is specific to tenascin-C C domain (TNC-C) |
| Synonyms | PL3, Tenascin-C C domain specific peptide |
| Relevance | Tenascin-C C domain (TNC-C) is not present in the extracellular matrix of adult tissues but it is up-regulated in tumours and malignant tissues. It has previously been used as a target for antibody-based therapies. PL3 is a specific peptide which has enhanced affinity to bind to TNC-C so PL3 may be useful as an affinity ligand for delivery of diagnostic compound into solid tumours. |
| Antigen/Gene or Protein Targets | Tenascin-C C domain (TNC-C) |
| Research Area | Cancer, Extracellular Matrix |
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Inventor Information
Inventors
|
Prakash Lingasamy |
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Tambet Teesalu |
