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DLKP-M cell line
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Invented by Martin Clynes at Dublin City University

Info

Catalogue Number 157660
Antigen/Gene or Protein Targets DLKP
Parental Line DLKP
Host Human
Tissue Lung
Disease Keywords Lung carcinoma
Relevance Mesenchymal-like sub-population cloned at NCTCC from DLKP P5, about 5% of DLKP cells show DLKP-M morphology, interconversion with -I, closest to normal chromosome number, fold resistance comp. to DLKP: 0.8 Adr; 0.95 Vcr; 0.7 VP-16. Immunocytochemistry: cytokeratin (all)-; GFAP-vimentin+; neurofilament+; P-gp-; a2- integrin++; 703D4+; 704A1 +; desmin-. More invasive in vitro than DLKP-SQ.
Production Details Single cell cloning from DLKP parental population
Research Area Cancer
Growth/Phenotype Keywords Monolayer
Recommended Growing Conditions DMEM/Ham's F12, 5% FCS. Split 1:5, medium change 2-3 times weekly. Freezing method: 10% DMSO in FBS
Positive Control DLKP
Cellosaurus ID CVCL_H739

References

There are 3 reference entries for this reagent.

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References: 3 entries

O'Sullivan et al. 2014. Tumour Biol. 35(7):6983-97. PMID: 24744142.

Keenan et al. 2012. Exp Cell Res. 318(5):593-602. PMID: 22281030.

McBride et al. 1998. Tumour Biol. 19(2):88-103. PMID: 9486560.


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References: 3 entries

O'Sullivan et al. 2014. Tumour Biol. 35(7):6983-97. PMID: 24744142.

Keenan et al. 2012. Exp Cell Res. 318(5):593-602. PMID: 22281030.

McBride et al. 1998. Tumour Biol. 19(2):88-103. PMID: 9486560.


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Inventor Information