Anti-Human Ataxin-3 [4B8] monoclonal antibody
Invented by Dr. Patrick Loll
Invented at Drexel University
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Info
| Catalogue Number | 156506 |
| Applications | ELISA IP |
| Antigen/Gene or Protein Targets | Ataxin-3 |
| Synonyms | Machado-Joseph Disease (MJD) Protein 1; Spinocerebellar Ataxia Type 3 |
| Reactivity | Human |
| Relevance | Ataxin-3 is a deubiquitinating enzyme involved in the clearance of misfolded proteins. The enzyme functions in proteasome degradation and autophagy. Mutated forms of Ataxin-3 can lead to misfolded protein aggregation which cause the neurodegenerative disorder spinocerebellar ataxia type-3 (SCA3), also known as Machado-Joseph disease. |
| Host | Mouse |
| Immunogen | Recombinant Human Ataxin-3 |
| Immunogen UniProt ID | ATX3_HUMAN |
| Positive Control | IgG1 kappa |
| Molecular Weight (kDa) | 42 |
| Research Area | Neurobiology, Protein Degradation |
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Inventor Information
Inventors
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Dr. Patrick Loll |
