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Anti-Human Ataxin-3 [4B8] monoclonal antibody
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Invented by Dr. Patrick Loll at Drexel University

Info

Catalogue Number 156506
Applications ELISA IP
Antigen/Gene or Protein Targets Ataxin-3
Synonyms Machado-Joseph Disease (MJD) Protein 1; Spinocerebellar Ataxia Type 3
Reactivity Human
Relevance Ataxin-3 is a deubiquitinating enzyme involved in the clearance of misfolded proteins. The enzyme functions in proteasome degradation and autophagy. Mutated forms of Ataxin-3 can lead to misfolded protein aggregation which cause the neurodegenerative disorder spinocerebellar ataxia type-3 (SCA3), also known as Machado-Joseph disease.
Host Mouse
Immunogen Recombinant Human Ataxin-3
Immunogen UniProt ID ATX3_HUMAN
Positive Control IgG1 kappa
Molecular Weight (kDa) 42
Research Area Neurobiology, Protein Degradation

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