#156506

Anti-Human Ataxin-3 [4B8]

Cat. #156506

Anti-Human Ataxin-3 [4B8]

Cat. #: 156506

Sub-type: Primary antibody

Unit size: 100 ug

Availability: 3-4 weeks

Target: Ataxin-3

Class: Monoclonal

Application: ELISA ; IP

Reactivity: Human

Host: Mouse

£300.00

This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.

Contributor

Inventor: Patrick Loll

Institute: Drexel University

Tool Details
Target Details
Applications
Handling

Tool Details

*FOR RESEARCH USE ONLY

  • Name: Anti-Human Ataxin-3 [4B8]
  • Alternate name: Machado-Joseph Disease (MJD) Protein 1; Spinocerebellar Ataxia Type 3
  • Tool sub type: Primary antibody
  • Class: Monoclonal
  • Purpose: Marker
  • Conjugation: Unconjugated
  • Cell signalling pathway: PI3K signalling
  • Molecular weight: 42 kDa
  • Reactivity: Human
  • Host: Mouse
  • Application: ELISA ; IP
  • Description: Ataxin-3 is a deubiquitinating enzyme involved in the clearance of misfolded proteins. The enzyme functions in proteasome degradation and autophagy. Mutated forms of Ataxin-3 can lead to misfolded protein aggregation which cause the neurodegenerative disorder spinocerebellar ataxia type-3 (SCA3), also known as Machado-Joseph disease.
  • Immunogen: Recombinant Human Ataxin-3
  • Immunogen uniprot id: ATX3_HUMAN
  • Recommended controls: IgG1 kappa

Target Details

  • Target: Ataxin-3
  • Molecular weight: 42 kDa
  • Tissue cell line specificity: Mouse
  • Target background: Ataxin-3 is a deubiquitinating enzyme involved in the clearance of misfolded proteins. The enzyme functions in proteasome degradation and autophagy. Mutated forms of Ataxin-3 can lead to misfolded protein aggregation which cause the neurodegenerative disorder spinocerebellar ataxia type-3 (SCA3), also known as Machado-Joseph disease.

Applications

  • Application: ELISA ; IP

Handling

  • Format: Liquid
  • Concentration: 0.9-1.1 mg/ml
  • Unit size: 100 ug
  • Storage buffer: PBS with 0.02% azide
  • Storage conditions: -15° C to -25° C
  • Shipping conditions: Shipping at 4° C