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Catalogue Number
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156495 |
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Antigen/Gene or Protein Targets
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This conjugate targets aminopeptidase N and exerts an antitumor effect in hepatocellular carcinoma stem cells
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Type
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Inhibitor
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Relevance
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The molecule exerts stronger inhibitory effect at lower concentrations that Ube alone,suggesting that PLys conjugation effectively increases the antitumor effect in HCC cells, presumably by targeting APN/CD13+cells, and enhances the strength of molecule-to-cell interactions.
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Research Area
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Drug Discovery & Development, Cancer
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