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PlasmaxTM cell culture medium

Invented by Saverio Tardito at Cancer Research UK Glasgow: The Beatson Institute

Info

Catalogue Number 156371
Relevance Background and Research Application

PlasmaxTM is a new physiologically relevant cell culture medium which mimics the metabolic and physiological profile of human plasma. It is designed to improve the metabolic fidelity and biological relevance of in vitro cancer models by recapitulating the natural in vivo metabolic environment in an in vitro setting.

Researchers have found that conventional growth-focused media with non-physiological concentrations of nutrients and metabolites can skew the metabolic profile of cancer cells. PlasmaxTM was created to address this problem as it is optimised to reflect natural concentrations of over 80 compounds found in human plasma. These include amino acids and derivatives, inorganic salts, trace elements, and vitamins.

PlasmaxTM can be used by cancer researchers interested in cancer cell biology. It has been validated for growth performance and metabolic fidelity in several widely-used triple-negative breast cancer cell lines.

PlasmaxTM formulation compared to conventional media.
Volume (mL) 500
Notes PlasmaxTM is a complete and ready-to-use cell culture medium.

PlasmaxTM is stable for six months at 4°C.

References

There are 3 reference entries for this reagent.

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References: 3 entries

Ackermann et al. 2019. Trends Cancer. 5(6):329-332. PMID: 31208694.

Cell culture shock – a scientist’s hunt for the perfect cocktail

Vande Voorde et al. 2019. Sci Adv. 5(1):eaau7314. PMID: 30613774.


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References: 3 entries

Ackermann et al. 2019. Trends Cancer. 5(6):329-332. PMID: 31208694.

Cell culture shock – a scientist’s hunt for the perfect cocktail

Vande Voorde et al. 2019. Sci Adv. 5(1):eaau7314. PMID: 30613774.


Add a reference