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Catalogue Number
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154842 |
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Applications
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N/A
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Antigen/Gene or Protein Targets
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XRay Repair Cross Complementing 2 (XRCC2)
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Reactivity
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Hamster and Human
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Relevance
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X-Ray Repair Cross Complementing 2 (XRCC2) is a RAD51 paralog. RAD51 is a eukaryotic homologue of E. coli RecA, a recombinase, and a component of the homologous recombination DNA repair pathway. RAD51 forms a nucleoprotein filament (through binding RAD52 and single stranded DNA that are exposed following double strand breaks) that initiates recombination. XRCC2 is also a component of the homologous recombination pathway.
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Host
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Mouse
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Subclass
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IgG1
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Positive Control
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HeLa nuclear extracts
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Research Area
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Bacteriology, DNA Damage and Repair, Epigenetics & Nuclear Signalling
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Notes
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XRCC2 1G4/1 does not recognise other paralogs.
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