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Anti-CD8 [SPVT8] monoclonal Antibody
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Info

Catalogue Number 154794
Applications FACS IP
Antigen/Gene or Protein Targets CD8
Synonyms Leu2 T-Lymphocyte Antigen; OKT8 T-Cell Antigen
Reactivity Human
Relevance CD8 is a transmembrane glycoprotein that serves as a co-receptor for the T cell receptor (TCR). Like the TCR, CD8 binds to a major histocompatibility complex (MHC) molecule, but is specific for the class I MHC protein.
The CD8 co-receptor is predominantly expressed on the surface of cytotoxic T cells, but can also be found on natural killer cells, cortical thymocytes, and dendritic cells. The CD8 molecule is a marker for cytotoxic T cell population. It is expressed in T cell lymphoblastic lymphoma and hypo-pigmented mycosis fungoides
Host Mouse
Immunogen Human cytotoxic T-lymphocytes
Subclass IgG1
Molecular Weight (kDa) 32
Myeloma Used Sp2/0-Ag14
Strain Balb/c
Notes Fusion partners: SP2/0 x spleen cells origin BALB/C.
Research Area Cell Type or Organelle Marker, Immunology

References

There are 2 reference entries for this reagent.

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References: 2 entries

de Vries et al. 1984. J Immunol. 132(1):510-9. PMID: 6197458.

Spits et al. 1983. Hybridoma. 2(4):423-37. PMID: 6332061.


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References: 2 entries

de Vries et al. 1984. J Immunol. 132(1):510-9. PMID: 6197458.

Spits et al. 1983. Hybridoma. 2(4):423-37. PMID: 6332061.


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Inventor Information

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