Cat. #154794
Anti-CD8 [SPVT8]
Cat. #: 154794
Sub-type: Primary antibody
Unit size: 100 ug
Availability: 10-12 weeks
Target: CD8
Class: Monoclonal
Application: FACS ; IP
Reactivity: Human
Host: Mouse
£300.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Institute: Netherlands Cancer Institute
Tool Details
*FOR RESEARCH USE ONLY
- Name: Anti-CD8 [SPVT8]
- Alternate name: Leu2 T-Lymphocyte Antigen; OKT8 T-Cell Antigen
- Tool sub type: Primary antibody
- Class: Monoclonal
- Conjugation: Unconjugated
- Molecular weight: 32 kDa
- Strain: Balb/c
- Reactivity: Human
- Host: Mouse
- Application: FACS ; IP
- Description: CD8 is a transmembrane glycoprotein that serves as a co-receptor for the T cell receptor (TCR). Like the TCR, CD8 binds to a major histocompatibility complex (MHC) molecule, but is specific for the class I MHC protein. The CD8 co-receptor is predominantly expressed on the surface of cytotoxic T cells, but can also be found on natural killer cells, cortical thymocytes, and dendritic cells. The CD8 molecule is a marker for cytotoxic T cell population. It is expressed in T cell lymphoblastic lymphoma and hypo-pigmented mycosis fungoides
- Immunogen: Human cytotoxic T-lymphocytes
- Isotype: IgG1
- Myeloma used: Sp2/0-Ag14
Target Details
- Target: CD8
- Molecular weight: 32 kDa
- Target background: CD8 is a transmembrane glycoprotein that serves as a co-receptor for the T cell receptor (TCR). Like the TCR, CD8 binds to a major histocompatibility complex (MHC) molecule, but is specific for the class I MHC protein. The CD8 co-receptor is predominantly expressed on the surface of cytotoxic T cells, but can also be found on natural killer cells, cortical thymocytes, and dendritic cells. The CD8 molecule is a marker for cytotoxic T cell population. It is expressed in T cell lymphoblastic lymphoma and hypo-pigmented mycosis fungoides
Applications
- Application: FACS ; IP
Handling
- Format: Liquid
- Concentration: 0.9-1.1 mg/ml
- Unit size: 100 ug
- Storage buffer: PBS with 0.02% azide
- Storage conditions: -15° C to -25° C
- Shipping conditions: Shipping at 4° C
References
- de Vries et al. 1984. J Immunol. 132(1):510-9. PMID: 6197458.
- Spits et al. 1983. Hybridoma. 2(4):423-37. PMID: 6332061.
