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Anti-Keratin 14 [SPK14] monoclonal Antibody
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Catalogue Number 154748
Applications FACS IHC WB
Antigen/Gene or Protein Targets Keratin14
Synonyms KRT14; Keratin 14
Reactivity Human, Pig and Feline
Relevance Cytokeratin 14 is a member of the type I keratin family of intermediate filament proteins. Cytokeratin 14 is usually found as a heterodimer with type II keratin 5 and form the cytoskeleton of epithelial cells. Mutations in the genes for these keratins are associated with epidermolysis bullosa simplex and dermatopathia pigmentosa reticularis, both of which are autosomal dominant mutations
Host Mouse
Immunogen Mouse was immunized with a synthetic peptide corresponding to the carboxy-terminal sequence of human cytokeratin 14 (KVVSTHEQVLRTKN) coupled to keyhole limpet hemocyanin.
Subclass IgG1
Molecular Weight (kDa) 51
Myeloma Used Sp2/0-Ag14
Recommended Growing Conditions IMDM + 1% ZAP, 37 ⁰C 5% CO2
Strain Balb/c
Notes Fusion partners: SP2/0 x spleen cells origin BALB/C. Reacts exclusively with cytokeratin 14 which is present in basal cell compartments of stratified and combined epithelia.
Research Area Cell Structure and Motility

References

There are 2 reference entries for this reagent.

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References: 2 entries

Ivanyi et al. 1993. Am J Vet Res. 54(7):1095-102. PMID: 7690208.

Ivanyi et al. 1992. Am J Vet Res. 53(3):304-14. PMID: 1375818.


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References: 2 entries

Ivanyi et al. 1993. Am J Vet Res. 54(7):1095-102. PMID: 7690208.

Ivanyi et al. 1992. Am J Vet Res. 53(3):304-14. PMID: 1375818.


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