Anti-Keratin 14 [SPK14]

Tool Details

*FOR RESEARCH USE ONLY

• Name: Anti-Keratin 14 [SPK14]
• Alternate name: KRT14; Keratin 14
• Tool sub type: Primary antibody
• Class: Monoclonal
• Conjugation: Unconjugated
• Molecular weight: 51 kDa
• Strain: Balb/c
• Reactivity: Human ; Pig ; Feline
• Host: Mouse
• Application: FACS ; IHC ; WB
• Description: Cytokeratin 14 is a member of the type I keratin family of intermediate filament proteins. Cytokeratin 14 is usually found as a heterodimer with type II keratin 5 and form the cytoskeleton of epithelial cells. Mutations in the genes for these keratins are associated with epidermolysis bullosa simplex and dermatopathia pigmentosa reticularis, both of which are autosomal dominant mutations
• Immunogen: Mouse was immunized with a synthetic peptide corresponding to the carboxy-terminal sequence of human cytokeratin 14 (KVVSTHEQVLRTKN) coupled to keyhole limpet hemocyanin.
• Isotype: IgG1
• Myeloma used: Sp2/0-Ag14

Target Details

• Target: Keratin14
• Molecular weight: 51 kDa
• Target background: Cytokeratin 14 is a member of the type I keratin family of intermediate filament proteins. Cytokeratin 14 is usually found as a heterodimer with type II keratin 5 and form the cytoskeleton of epithelial cells. Mutations in the genes for these keratins are associated with epidermolysis bullosa simplex and dermatopathia pigmentosa reticularis, both of which are autosomal dominant mutations

Applications

• Application: FACS ; IHC ; WB

Handling

• Format: Liquid
• Concentration: 0.9-1.1 mg/ml
• Unit size: 100 ug
• Storage buffer: PBS with 0.02% azide
• Storage conditions: -15° C to -25° C
• Shipping conditions: Shipping at 4° C

References

• Ivanyi et al. 1993. Am J Vet Res. 54(7):1095-102. PMID: 7690208.
• Ivanyi et al. 1992. Am J Vet Res. 53(3):304-14. PMID: 1375818.