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Anti-Big (high-molecular-weight) tau, Polyclonal antibody

Info

Catalogue Number 154129
Applications IHC WB
Antigen/Gene or Protein Targets Big tau (high-molecular-weight)
Reactivity Rat
Relevance Tau is a neuronal microtubule associated protein (MAP) which has multiple isoforms that are differentially expressed during development. Big tau is a high molecular weight isoform that contains an additional large exon (4a) and is expressed primarily by neurons in the peripheral nervous system. Big tau expression has also been shown in the developing spinal cord and in the adult central nervous system. Big tau may be important in stabilizing microtubules in axons that are subjected to great shear forces.
Host Rabbit
Immunogen Recombinant protein of the complete 4a exon of tau, specific to the Big tau isoform, was used to produce antibody
Research Area Developmental Biology, Neurobiology

References

There are 2 reference entries for this reagent.

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References: 2 entries

Boyne et al. 1995. J Comp Neurol. 358(2):279-93. PMID: 7560287.

Distribution of Big tau in the central nervous system of the adult and developing rat.

Europe PMC ID: 7560287


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References: 2 entries

Boyne et al. 1995. J Comp Neurol. 358(2):279-93. PMID: 7560287.

Distribution of Big tau in the central nervous system of the adult and developing rat.


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Inventor Information

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