Msh3-/- SVG-A Cell Line
Invented by Prof Robert Lahue at National University of Ireland, Galway Brown University
SVG-A Msh3 1.7X Cell Line
Invented by Prof Robert Lahue from National University of Ireland, Galway
Invented at National University of Ireland, Galway , Brown University
- Datasheet
- References (1)
- Inventor Info
Info
| Catalogue Number | 153691 |
| Parental Line | Msh3-/- SVG-A Cell Line |
| Host | Human |
| Tissue | Brain |
| Relevance | This cell line was derived from the SVG-A Msh3-/- (knock-out generated by CRISPR)) cell line whereby the DNA mismatch repair protein Msh3 expression has been reinstated. |
| Research Area | DNA Damage and Repair, Neurobiology, Virology |
| Recommended Growing Conditions | DMEM supplemented with 10% FBS |
| Notes |
CRISPR edited cells. Cancer Research Technology Limited (trading research tools as Ximbio) has been granted a non-exclusive license to the CRISPR-Cas9 technology by ERS Genomics Ltd under the patent rights listed here. This license from ERS Genomics Ltd allows Ximbio to develop and commercialise CRISPR-Cas9 modified cell lines for research use only. Ximbio can provide these modified CRISPR-Cas9 cell lines to companies under a label-use only license. |
SVG-A Cell Line
Invented at Brown University
References: 1 entry
Keogh et al. 2017. MutSβ abundance and Msh3 ATP hydrolysis activity are important drivers of CTG•CAG repeat expansions. Nucleic Acids Res. 2017 Sep 29;45(17):10068-10078.
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References: 1 entry
Keogh et al. 2017. MutSβ abundance and Msh3 ATP hydrolysis activity are important drivers of CTG•CAG repeat expansions. Nucleic Acids Res. 2017 Sep 29;45(17):10068-10078.
Add a reference
