Anti-Follistatin 288 [29/9]
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- References (20)
- Inventor Info
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| Catalogue Number | 153636 |
| Applications | ELISA |
| Antigen/Gene or Protein Targets | Follistation 288 |
| Synonyms | Follistatin, FS, FST, Active-binding protein |
| Reactivity | Human |
| Relevance | Follistatin is a single-chain glycosylated protein that inhibits follicle stimulating hormone (FSH) release. Alternative splicing of Follistatin mRNA yields two isoforms, FS315 and FS288. FS288 is the main cell-surface form and binds to surface heparin sulphate proteoglycans. 29/9 is a clone raised against recombinant Fst 288, and is used in combination, commonly as the capture, with antibody 17/2 in a two site ELISA for the detection of Follistatin. |
| Host | Mouse |
| Immunogen | Raised to human Follistatin (Fst) 288 and recognizes both human Fst 288 and 315 |
| Positive Control | Testis or Ovary |
| Subclass | IgG1 |
| Molecular Weight (kDa) | 37 |
| Myeloma Used | Sp2/0-Ag14 |
| Strain | Balb/c |
| Notes |
Suggested dilutions for use Two-site ELISA In combination with clone 17/2 Research Areas: Endocrinology;Cancer;Fertility;Hepatology;Apoptosis and Programmed Cell Death;Cell Signaling & Signal Transduction;Epigenetics & Nuclear Signalling |
| Research Area | Apoptosis and Programmed Cell Death, Cancer, Cell Signaling & Signal Transduction, Epigenetics & Nuclear Signalling |
References: 20 entries
Hughes et al. 2003. Eur J Gastroenterol Hepatol. 15(2):127-31. PMID: 12560755.
Activin A and follistatin in acute liver failure.
Europe PMC ID: 12560755
Yuen et al. 2002. Scand J Gastroenterol. 37(2):233-8. PMID: 11843063.
Transforming growth factor-beta 1, activin and follistatin in patients with hepatocellular carcinoma and patients with alcoholic cirrhosis.
Europe PMC ID: 11843063
Menon et al. 2000. BJOG. 107(9):1069-74. PMID: 11002947.
Serum inhibin, activin and follistatin in postmenopausal women with epithelial ovarian carcinoma.
Europe PMC ID: 11002947
McPherson et al. 1999. Endocrinology. 140(11):5303-9. PMID: 10537161.
Expression of activin A and follistatin core proteins by human prostate tumor cell lines.
Europe PMC ID: 10537161
Cuckle et al. 1999. Prenat Diagn. 19(6):513-6. PMID: 10416964.
Maternal serum activin A and follistatin levels in pregnancies with Down syndrome.
Europe PMC ID: 10416964
Fowler et al. 1998. Hum Reprod. 13(12):3530-6. PMID: 9886545.
Anderson et al. 1998. Hum Reprod. 13(12):3319-25. PMID: 9886507.
Follistatin and activin A production by the male reproductive tract.
Europe PMC ID: 9886507
A longitudinal study of maternal serum inhibin-A, inhibin-B, activin-A, activin-AB, pro-alphaC and follistatin during pregnancy.
Europe PMC ID: 9886545
Riley et al. 1998. Hum Reprod. 13(9):2624-8. PMID: 9806296.
Follistatin and activin A in extra-embryonic coelomic and amniotic fluids and maternal serum in early pregnancy.
Europe PMC ID: 9806296
Evans et al. 1998. J Endocrinol. 156(2):275-82. PMID: 9518873.
Development, validation and application of an ultra-sensitive two-site enzyme immunoassay for human follistatin.
Europe PMC ID: 9518873
Petraglia et al. 1997. J Clin Endocrinol Metab. 82(9):2991-5. PMID: 9284732.
Changes of dimeric inhibin B levels in maternal serum throughout healthy gestation and in women with gestational diseases.
Europe PMC ID: 9284732
Add a reference
References: 20 entries
Hughes et al. 2003. Eur J Gastroenterol Hepatol. 15(2):127-31. PMID: 12560755.
Activin A and follistatin in acute liver failure.
Yuen et al. 2002. Scand J Gastroenterol. 37(2):233-8. PMID: 11843063.
Transforming growth factor-beta 1, activin and follistatin in patients with hepatocellular carcinoma and patients with alcoholic cirrhosis.
Menon et al. 2000. BJOG. 107(9):1069-74. PMID: 11002947.
Serum inhibin, activin and follistatin in postmenopausal women with epithelial ovarian carcinoma.
McPherson et al. 1999. Endocrinology. 140(11):5303-9. PMID: 10537161.
Expression of activin A and follistatin core proteins by human prostate tumor cell lines.
Cuckle et al. 1999. Prenat Diagn. 19(6):513-6. PMID: 10416964.
Maternal serum activin A and follistatin levels in pregnancies with Down syndrome.
Fowler et al. 1998. Hum Reprod. 13(12):3530-6. PMID: 9886545.
Anderson et al. 1998. Hum Reprod. 13(12):3319-25. PMID: 9886507.
Follistatin and activin A production by the male reproductive tract.
A longitudinal study of maternal serum inhibin-A, inhibin-B, activin-A, activin-AB, pro-alphaC and follistatin during pregnancy.
Riley et al. 1998. Hum Reprod. 13(9):2624-8. PMID: 9806296.
Follistatin and activin A in extra-embryonic coelomic and amniotic fluids and maternal serum in early pregnancy.
Evans et al. 1998. J Endocrinol. 156(2):275-82. PMID: 9518873.
Development, validation and application of an ultra-sensitive two-site enzyme immunoassay for human follistatin.
Petraglia et al. 1997. J Clin Endocrinol Metab. 82(9):2991-5. PMID: 9284732.
Changes of dimeric inhibin B levels in maternal serum throughout healthy gestation and in women with gestational diseases.
Add a reference