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Anti-Follistatin 288 [29/9]

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Info

Catalogue Number 153636
Applications ELISA
Antigen/Gene or Protein Targets Follistation 288
Synonyms Follistatin, FS, FST, Active-binding protein
Reactivity Human
Relevance Follistatin is a single-chain glycosylated protein that inhibits follicle stimulating hormone (FSH) release. Alternative splicing of Follistatin mRNA yields two isoforms, FS315 and FS288. FS288 is the main cell-surface form and binds to surface heparin sulphate proteoglycans. 29/9 is a clone raised against recombinant Fst 288, and is used in combination, commonly as the capture, with antibody 17/2 in a two site ELISA for the detection of Follistatin.
Host Mouse
Immunogen Raised to human Follistatin (Fst) 288 and recognizes both human Fst 288 and 315
Positive Control Testis or Ovary
Subclass IgG1
Molecular Weight (kDa) 37
Myeloma Used Sp2/0-Ag14
Strain Balb/c
Notes Suggested dilutions for use

Two-site ELISA In combination with clone 17/2

Research Areas: Endocrinology;Cancer;Fertility;Hepatology;Apoptosis and Programmed Cell Death;Cell Signaling & Signal Transduction;Epigenetics & Nuclear Signalling
Research Area Apoptosis and Programmed Cell Death, Cancer, Cell Signaling & Signal Transduction, Epigenetics & Nuclear Signalling

References

There are 20 reference entries for this reagent.

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References: 20 entries

Hughes et al. 2003. Eur J Gastroenterol Hepatol. 15(2):127-31. PMID: 12560755.

Activin A and follistatin in acute liver failure.

Europe PMC ID: 12560755

Yuen et al. 2002. Scand J Gastroenterol. 37(2):233-8. PMID: 11843063.

Transforming growth factor-beta 1, activin and follistatin in patients with hepatocellular carcinoma and patients with alcoholic cirrhosis.

Europe PMC ID: 11843063

Menon et al. 2000. BJOG. 107(9):1069-74. PMID: 11002947.

Serum inhibin, activin and follistatin in postmenopausal women with epithelial ovarian carcinoma.

Europe PMC ID: 11002947

McPherson et al. 1999. Endocrinology. 140(11):5303-9. PMID: 10537161.

Expression of activin A and follistatin core proteins by human prostate tumor cell lines.

Europe PMC ID: 10537161

Cuckle et al. 1999. Prenat Diagn. 19(6):513-6. PMID: 10416964.

Maternal serum activin A and follistatin levels in pregnancies with Down syndrome.

Europe PMC ID: 10416964

Fowler et al. 1998. Hum Reprod. 13(12):3530-6. PMID: 9886545.

Anderson et al. 1998. Hum Reprod. 13(12):3319-25. PMID: 9886507.

Follistatin and activin A production by the male reproductive tract.

Europe PMC ID: 9886507

A longitudinal study of maternal serum inhibin-A, inhibin-B, activin-A, activin-AB, pro-alphaC and follistatin during pregnancy.

Europe PMC ID: 9886545

Riley et al. 1998. Hum Reprod. 13(9):2624-8. PMID: 9806296.

Follistatin and activin A in extra-embryonic coelomic and amniotic fluids and maternal serum in early pregnancy.

Europe PMC ID: 9806296

Evans et al. 1998. J Endocrinol. 156(2):275-82. PMID: 9518873.

Development, validation and application of an ultra-sensitive two-site enzyme immunoassay for human follistatin.

Europe PMC ID: 9518873

Petraglia et al. 1997. J Clin Endocrinol Metab. 82(9):2991-5. PMID: 9284732.

Changes of dimeric inhibin B levels in maternal serum throughout healthy gestation and in women with gestational diseases.

Europe PMC ID: 9284732


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References: 20 entries

Hughes et al. 2003. Eur J Gastroenterol Hepatol. 15(2):127-31. PMID: 12560755.

Activin A and follistatin in acute liver failure.

Yuen et al. 2002. Scand J Gastroenterol. 37(2):233-8. PMID: 11843063.

Transforming growth factor-beta 1, activin and follistatin in patients with hepatocellular carcinoma and patients with alcoholic cirrhosis.

Menon et al. 2000. BJOG. 107(9):1069-74. PMID: 11002947.

Serum inhibin, activin and follistatin in postmenopausal women with epithelial ovarian carcinoma.

McPherson et al. 1999. Endocrinology. 140(11):5303-9. PMID: 10537161.

Expression of activin A and follistatin core proteins by human prostate tumor cell lines.

Cuckle et al. 1999. Prenat Diagn. 19(6):513-6. PMID: 10416964.

Maternal serum activin A and follistatin levels in pregnancies with Down syndrome.

Fowler et al. 1998. Hum Reprod. 13(12):3530-6. PMID: 9886545.

Anderson et al. 1998. Hum Reprod. 13(12):3319-25. PMID: 9886507.

Follistatin and activin A production by the male reproductive tract.

A longitudinal study of maternal serum inhibin-A, inhibin-B, activin-A, activin-AB, pro-alphaC and follistatin during pregnancy.

Riley et al. 1998. Hum Reprod. 13(9):2624-8. PMID: 9806296.

Follistatin and activin A in extra-embryonic coelomic and amniotic fluids and maternal serum in early pregnancy.

Evans et al. 1998. J Endocrinol. 156(2):275-82. PMID: 9518873.

Development, validation and application of an ultra-sensitive two-site enzyme immunoassay for human follistatin.

Petraglia et al. 1997. J Clin Endocrinol Metab. 82(9):2991-5. PMID: 9284732.

Changes of dimeric inhibin B levels in maternal serum throughout healthy gestation and in women with gestational diseases.


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