Anti-Follistatin 315 [H10]
Invented at
- Datasheet
- References (6)
- Inventor Info
Info
![Image thumbnail for Anti-Follistatin 315 [H10]](https://res.cloudinary.com/ximbio/image/upload/c_fit,fl_lossy,h_45,q_auto/e72362c2-8aa1-4fde-a096-0f0eace6e3fd.png)
![Image thumbnail for Anti-Follistatin 315 [H10]](https://res.cloudinary.com/ximbio/image/upload/c_fit,fl_lossy,h_45,q_auto/5bac2aa1-e0a9-4cf7-8a82-dffc52c63599.png)
![Image thumbnail for Anti-Follistatin 315 [H10]](https://res.cloudinary.com/ximbio/image/upload/c_fit,fl_lossy,h_45,q_auto/92b90c8b-1a77-411d-8452-e5f2c9e1655a.png)
| Catalogue Number | 153635 |
| Applications | ELISA IHC WB |
| Antigen/Gene or Protein Targets | Follistatin 315 |
| Synonyms | Follistatin, FS, FST, Active-binding protein |
| Reactivity | Human |
| Relevance | Follistatin is a single-chain glycosylated protein that inhibits follicle stimulating hormone (FSH) release. Alternative splicing of Follistatin mRNA yields two isoforms, FS315 and FS288. FS315 is considered the main circulating form of Follistatin. Clone H10 recognizes an epitope on the C-terminal region of human Follistatin 315, allowing for detection of FSH levels using various analysis methods. ELISA experiments showed that H10 interacts with FS315 and does not interact with FS288. |
| Host | Mouse |
| Immunogen | Synthetic peptide corresponding to sequence CDEDQDYSFPISSILEW of the C- terminal region of human Follistatin 315 |
| Positive Control | Testis |
| Subclass | IgG2a |
| Molecular Weight (kDa) | 37 |
| Myeloma Used | Sp2/0-Ag14 |
| Notes |
Suggested dilutions for use Western Blot 1 μg/mL Immunohistochemistry 1:100 ELISA Assay-dependent Research Areas: Endocrinology;Cancer;Fertility;Hepatology;Immunology;Neurobiology;Cell Signaling & Signal Transduction;Epigenetics & Nuclear Signalling;Stem Cell Biology |
| Research Area | Cancer, Cell Signaling & Signal Transduction, Epigenetics & Nuclear Signalling, Immunology, Neurobiology, Stem Cell Biology |
References: 6 entries
Fitzgerald et al. 2012. Invest Ophthalmol Vis Sci. 53(11):7358-69. PMID: 23010638.
The effects of transforming growth factor-β2 on the expression of follistatin and activin A in normal and glaucomatous human trabecular meshwork cells and tissues.
Europe PMC ID: 23010638
Praticò et al. 2004. Chem Phys Lipids. 128(1-2):165-71. PMID: 15037161.
F2-isoprostanes as indices of lipid peroxidation in inflammatory diseases.
Europe PMC ID: 15037161
Cancilla et al. 2001. Dev Biol. 237(1):145-58. PMID: 11518512.
Regulation of prostate branching morphogenesis by activin A and follistatin.
Europe PMC ID: 11518512
Add a reference
References: 6 entries
Fitzgerald et al. 2012. Invest Ophthalmol Vis Sci. 53(11):7358-69. PMID: 23010638.
The effects of transforming growth factor-β2 on the expression of follistatin and activin A in normal and glaucomatous human trabecular meshwork cells and tissues.
Praticò et al. 2004. Chem Phys Lipids. 128(1-2):165-71. PMID: 15037161.
F2-isoprostanes as indices of lipid peroxidation in inflammatory diseases.
Cancilla et al. 2001. Dev Biol. 237(1):145-58. PMID: 11518512.
Regulation of prostate branching morphogenesis by activin A and follistatin.
Add a reference