#153635

Anti-Follistatin 315 [H10]

Cat. #153635

Anti-Follistatin 315 [H10]

Cat. #: 153635

Sub-type: Primary antibody

Unit size: 100 ug

Availability: 10-12 weeks

Target: Follistatin 315

Class: Monoclonal

Application: ELISA ; IHC ; WB

Reactivity: Human

Host: Mouse

£300.00

This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.

Contributor

Institute: BioServ UK Ltd

Tool Details
Target Details
Applications
Handling
References

Tool Details

*FOR RESEARCH USE ONLY

  • Name: Anti-Follistatin 315 [H10]
  • Alternate name: Follistatin, FS, FST, Active-binding protein
  • Clone: H10
  • Tool sub type: Primary antibody
  • Class: Monoclonal
  • Conjugation: Unconjugated
  • Molecular weight: 37 kDa
  • Reactivity: Human
  • Host: Mouse
  • Application: ELISA ; IHC ; WB
  • Description: Follistatin is a single-chain glycosylated protein that inhibits follicle stimulating hormone (FSH) release. Alternative splicing of Follistatin mRNA yields two isoforms, FS315 and FS288. FS315 is considered the main circulating form of Follistatin. Clone H10 recognizes an epitope on the C-terminal region of human Follistatin 315, allowing for detection of FSH levels using various analysis methods. ELISA experiments showed that H10 interacts with FS315 and does not interact with FS288.
  • Immunogen: Synthetic peptide corresponding to sequence CDEDQDYSFPISSILEW of the C- terminal region of human Follistatin 315
  • Isotype: IgG2a
  • Myeloma used: Sp2/0-Ag14
  • Recommended controls: Testis

Target Details

  • Target: Follistatin 315
  • Molecular weight: 37 kDa
  • Tissue cell line specificity: Testis
  • Target background: Follistatin is a single-chain glycosylated protein that inhibits follicle stimulating hormone (FSH) release. Alternative splicing of Follistatin mRNA yields two isoforms, FS315 and FS288. FS315 is considered the main circulating form of Follistatin. Clone H10 recognizes an epitope on the C-terminal region of human Follistatin 315, allowing for detection of FSH levels using various analysis methods. ELISA experiments showed that H10 interacts with FS315 and does not interact with FS288.

Applications

  • Application: ELISA ; IHC ; WB

Handling

  • Format: Liquid
  • Unit size: 100 ug
  • Shipping conditions: Shipping at 4° C

References

  • Fitzgerald et al. 2012. Invest Ophthalmol Vis Sci. 53(11):7358-69. PMID: 23010638.
  • The effects of transforming growth factor-?2 on the expression of follistatin and activin A in normal and glaucomatous human trabecular meshwork cells and tissues.
  • Pratic et al. 2004. Chem Phys Lipids. 128(1-2):165-71. PMID: 15037161.
  • F2-isoprostanes as indices of lipid peroxidation in inflammatory diseases.
  • Cancilla et al. 2001. Dev Biol. 237(1):145-58. PMID: 11518512.
  • Regulation of prostate branching morphogenesis by activin A and follistatin.