Anti-Follistatin 288 [17-2]
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- References (12)
- Inventor Info
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| Catalogue Number | 153634 |
| Applications | ELISA IHC WB |
| Antigen/Gene or Protein Targets | Follistation 288 |
| Synonyms | Follistatin, FS, FST, Active-binding protein |
| Reactivity | Human |
| Relevance | Follistatin is a single-chain glycosylated protein that inhibits follicle stimulating hormone (FSH) release. Alternative splicing of Follistatin mRNA yields two isoforms, FS315 and FS288. FS288 is the main cell-surface form and binds to surface heparin sulphate proteoglycans. Clone 17/2 recognizes recombinant human Follistatin 288, allowing for detection of FSH levels using various analysis methods. This antibody also works in a two site ELISA with Clone 29/9. |
| Host | Mouse |
| Immunogen | Recognizes human Follistatin isoform FS288, raised against recombinant human FS288 |
| Positive Control | Testis |
| Subclass | IgG1 |
| Molecular Weight (kDa) | 37 |
| Myeloma Used | Sp2/0-Ag14 |
| Strain | Balb/c |
| Notes |
Suggested dilutions for use Western Blot 1 μg/mL Immunohistochemistry 10 μg/mL ELISA 1 μg/mL Immunocytochemistry 70 μg/mL Research Areas: Endocrinology;Cancer;Fertility;Immunology;Neurobiology;Cell Signaling & Signal Transduction;Epigenetics & Nuclear Signalling |
| Research Area | Cancer, Cell Signaling & Signal Transduction, Epigenetics & Nuclear Signalling, Immunology, Neurobiology |
References: 12 entries
Hands et al. 2013. Anal Bioanal Chem. 405(23):7347-55. PMID: 23831829.
Investigating the rapid diagnosis of gliomas from serum samples using infrared spectroscopy and cytokine and angiogenesis factors.
Europe PMC ID: 23831829
Fitzgerald et al. 2012. Invest Ophthalmol Vis Sci. 53(11):7358-69. PMID: 23010638.
The effects of transforming growth factor-β2 on the expression of follistatin and activin A in normal and glaucomatous human trabecular meshwork cells and tissues.
Europe PMC ID: 23010638
Mabuchi et al. 2006. Oncol Rep. 15(2):291-6. PMID: 16391844.
Immunohistochemical localization of inhibin and activin subunits, activin receptors, and Smads in ovarian clear cell adenocarcinoma.
Europe PMC ID: 16391844
Praticò et al. 2004. Chem Phys Lipids. 128(1-2):165-71. PMID: 15037161.
F2-isoprostanes as indices of lipid peroxidation in inflammatory diseases.
Europe PMC ID: 15037161
Evans et al. 1998. J Endocrinol. 156(2):275-82. PMID: 9518873.
Development, validation and application of an ultra-sensitive two-site enzyme immunoassay for human follistatin.
Europe PMC ID: 9518873
Majdic et al. 1997. Endocrinology. 138(5):2136-47. PMID: 9112414.
Testicular expression of inhibin and activin subunits and follistatin in the rat and human fetus and neonate and during postnatal development in the rat.
Europe PMC ID: 9112414
Add a reference
References: 12 entries
Hands et al. 2013. Anal Bioanal Chem. 405(23):7347-55. PMID: 23831829.
Investigating the rapid diagnosis of gliomas from serum samples using infrared spectroscopy and cytokine and angiogenesis factors.
Fitzgerald et al. 2012. Invest Ophthalmol Vis Sci. 53(11):7358-69. PMID: 23010638.
The effects of transforming growth factor-β2 on the expression of follistatin and activin A in normal and glaucomatous human trabecular meshwork cells and tissues.
Mabuchi et al. 2006. Oncol Rep. 15(2):291-6. PMID: 16391844.
Immunohistochemical localization of inhibin and activin subunits, activin receptors, and Smads in ovarian clear cell adenocarcinoma.
Praticò et al. 2004. Chem Phys Lipids. 128(1-2):165-71. PMID: 15037161.
F2-isoprostanes as indices of lipid peroxidation in inflammatory diseases.
Evans et al. 1998. J Endocrinol. 156(2):275-82. PMID: 9518873.
Development, validation and application of an ultra-sensitive two-site enzyme immunoassay for human follistatin.
Majdic et al. 1997. Endocrinology. 138(5):2136-47. PMID: 9112414.
Testicular expression of inhibin and activin subunits and follistatin in the rat and human fetus and neonate and during postnatal development in the rat.
Add a reference