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Anti-Follistatin 288 [17-2]

Info

Catalogue Number 153634
Applications ELISA IHC WB
Antigen/Gene or Protein Targets Follistation 288
Synonyms Follistatin, FS, FST, Active-binding protein
Reactivity Human
Relevance Follistatin is a single-chain glycosylated protein that inhibits follicle stimulating hormone (FSH) release. Alternative splicing of Follistatin mRNA yields two isoforms, FS315 and FS288. FS288 is the main cell-surface form and binds to surface heparin sulphate proteoglycans. Clone 17/2 recognizes recombinant human Follistatin 288, allowing for detection of FSH levels using various analysis methods. This antibody also works in a two site ELISA with Clone 29/9.
Host Mouse
Immunogen Recognizes human Follistatin isoform FS288, raised against recombinant human FS288
Positive Control Testis
Subclass IgG1
Molecular Weight (kDa) 37
Myeloma Used Sp2/0-Ag14
Strain Balb/c
Notes Suggested dilutions for use

Western Blot 1 μg/mL
Immunohistochemistry 10 μg/mL
ELISA 1 μg/mL
Immunocytochemistry 70 μg/mL

Research Areas: Endocrinology;Cancer;Fertility;Immunology;Neurobiology;Cell Signaling & Signal Transduction;Epigenetics & Nuclear Signalling
Research Area Cancer, Cell Signaling & Signal Transduction, Epigenetics & Nuclear Signalling, Immunology, Neurobiology

References

There are 12 reference entries for this reagent.

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References: 12 entries

Hands et al. 2013. Anal Bioanal Chem. 405(23):7347-55. PMID: 23831829.

Investigating the rapid diagnosis of gliomas from serum samples using infrared spectroscopy and cytokine and angiogenesis factors.

Europe PMC ID: 23831829

Fitzgerald et al. 2012. Invest Ophthalmol Vis Sci. 53(11):7358-69. PMID: 23010638.

The effects of transforming growth factor-β2 on the expression of follistatin and activin A in normal and glaucomatous human trabecular meshwork cells and tissues.

Europe PMC ID: 23010638

Mabuchi et al. 2006. Oncol Rep. 15(2):291-6. PMID: 16391844.

Immunohistochemical localization of inhibin and activin subunits, activin receptors, and Smads in ovarian clear cell adenocarcinoma.

Europe PMC ID: 16391844

Praticò et al. 2004. Chem Phys Lipids. 128(1-2):165-71. PMID: 15037161.

F2-isoprostanes as indices of lipid peroxidation in inflammatory diseases.

Europe PMC ID: 15037161

Evans et al. 1998. J Endocrinol. 156(2):275-82. PMID: 9518873.

Development, validation and application of an ultra-sensitive two-site enzyme immunoassay for human follistatin.

Europe PMC ID: 9518873

Majdic et al. 1997. Endocrinology. 138(5):2136-47. PMID: 9112414.

Testicular expression of inhibin and activin subunits and follistatin in the rat and human fetus and neonate and during postnatal development in the rat.

Europe PMC ID: 9112414


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References: 12 entries

Hands et al. 2013. Anal Bioanal Chem. 405(23):7347-55. PMID: 23831829.

Investigating the rapid diagnosis of gliomas from serum samples using infrared spectroscopy and cytokine and angiogenesis factors.

Fitzgerald et al. 2012. Invest Ophthalmol Vis Sci. 53(11):7358-69. PMID: 23010638.

The effects of transforming growth factor-β2 on the expression of follistatin and activin A in normal and glaucomatous human trabecular meshwork cells and tissues.

Mabuchi et al. 2006. Oncol Rep. 15(2):291-6. PMID: 16391844.

Immunohistochemical localization of inhibin and activin subunits, activin receptors, and Smads in ovarian clear cell adenocarcinoma.

Praticò et al. 2004. Chem Phys Lipids. 128(1-2):165-71. PMID: 15037161.

F2-isoprostanes as indices of lipid peroxidation in inflammatory diseases.

Evans et al. 1998. J Endocrinol. 156(2):275-82. PMID: 9518873.

Development, validation and application of an ultra-sensitive two-site enzyme immunoassay for human follistatin.

Majdic et al. 1997. Endocrinology. 138(5):2136-47. PMID: 9112414.

Testicular expression of inhibin and activin subunits and follistatin in the rat and human fetus and neonate and during postnatal development in the rat.


Add a reference

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