Anti-CD195 [HEK/1/85a/7a]
Invented at University Of Reading
- Datasheet
- References (2)
- Inventor Info
Info
| Catalogue Number | 153524 |
| Applications | FACS IF Fn |
| Antigen/Gene or Protein Targets | CD195 |
| Synonyms | Anti-CCR5, CCR5 Antibody, CD195 Antibody, C-C chemokine receptor type 5, HIV-1 fusion co-receptor |
| Reactivity | Human |
| Relevance | CD195 or CCR5 (CC-chemokine receptor type 5) is a receptor for a number of inflammatory CC-chemokines including MIP-1-alpha, MIP-1-beta and RANTES and subsequently transduces a signal by increasing the intracellular calcium ion level. It may play a role in the control of granulocytic lineage proliferation or differentiation, and has been shown to act as a co-receptor for HIV-1 R5 isolates. Recent studies have shown CCR5 to play a role in a variety of other human diseases, ranging from infectious and inflammatory diseases to cancer. |
| Host | Rat |
| Immunogen | CHO cells transfected with human CCR5 |
| Subclass | IgG2a kappa |
| Myeloma Used | Y3.AG.1.2.3 |
| Research Area | Immunology, Virology |
References: 2 entries
Mueller et al. 2002. Blood. 99(3):785-91. PMID: 11806977.
FACS IF
Pathways for internalization and recycling of the chemokine receptor CCR5.
Europe PMC ID: 11806977
Add a reference
References: 2 entries
Mueller et al. 2002. Blood. 99(3):785-91. PMID: 11806977.
FACS IF
Pathways for internalization and recycling of the chemokine receptor CCR5.
Add a reference
