Cat. #153524
Anti-CD195 [HEK/1/85a/7a]
Cat. #: 153524
Sub-type: Primary antibody
Unit size: 100 ug
Availability: 3-4 weeks
Target: CD195
Class: Monoclonal
Application: FACS ; IF ; Fn
Reactivity: Human
Host: Rat
£300.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Institute: University of Reading
Tool Details
*FOR RESEARCH USE ONLY
- Name: Anti-CD195 [HEK/1/85a/7a]
- Alternate name: Anti-CCR5, CCR5 Antibody, CD195 Antibody, C-C chemokine receptor type 5, HIV-1 fusion co-receptor
- Clone: HEK/1/85a/7a
- Tool sub type: Primary antibody
- Class: Monoclonal
- Conjugation: Unconjugated
- Reactivity: Human
- Host: Rat
- Application: FACS ; IF ; Fn
- Description: CD195 or CCR5 (CC-chemokine receptor type 5) is a receptor for a number of inflammatory CC-chemokines including MIP-1-alpha, MIP-1-beta and RANTES and subsequently transduces a signal by increasing the intracellular calcium ion level. It may play a role in the control of granulocytic lineage proliferation or differentiation, and has been shown to act as a co-receptor for HIV-1 R5 isolates. Recent studies have shown CCR5 to play a role in a variety of other human diseases, ranging from infectious and inflammatory diseases to cancer.
- Immunogen: CHO cells transfected with human CCR5
- Isotype: IgG2a kappa
- Myeloma used: Y3.AG.1.2.3
Target Details
- Target: CD195
- Target background: CD195 or CCR5 (CC-chemokine receptor type 5) is a receptor for a number of inflammatory CC-chemokines including MIP-1-alpha, MIP-1-beta and RANTES and subsequently transduces a signal by increasing the intracellular calcium ion level. It may play a role in the control of granulocytic lineage proliferation or differentiation, and has been shown to act as a co-receptor for HIV-1 R5 isolates. Recent studies have shown CCR5 to play a role in a variety of other human diseases, ranging from infectious and inflammatory diseases to cancer.
Applications
- Application: FACS ; IF ; Fn
Handling
- Format: Liquid
- Concentration: 0.9-1.1 mg/ml
- Unit size: 100 ug
- Storage buffer: PBS with 0.02% azide
- Storage conditions: -15° C to -25° C
- Shipping conditions: Shipping at 4° C
References
- Mueller et al. 2002. Blood. 99(3):785-91. PMID: 11806977.
- Pathways for internalization and recycling of the chemokine receptor CCR5.
