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Anti-CD195 [HEK/1/85a/7a]

Info

Catalogue Number 153524
Applications FACS IF Fn
Antigen/Gene or Protein Targets CD195
Synonyms Anti-CCR5, CCR5 Antibody, CD195 Antibody, C-C chemokine receptor type 5, HIV-1 fusion co-receptor
Reactivity Human
Relevance CD195 or CCR5 (CC-chemokine receptor type 5) is a receptor for a number of inflammatory CC-chemokines including MIP-1-alpha, MIP-1-beta and RANTES and subsequently transduces a signal by increasing the intracellular calcium ion level. It may play a role in the control of granulocytic lineage proliferation or differentiation, and has been shown to act as a co-receptor for HIV-1 R5 isolates. Recent studies have shown CCR5 to play a role in a variety of other human diseases, ranging from infectious and inflammatory diseases to cancer.
Host Rat
Immunogen CHO cells transfected with human CCR5
Subclass IgG2a kappa
Myeloma Used Y3.AG.1.2.3
Research Area Immunology, Virology

References: 1 entry

Mueller et al. 2002. Blood. 99(3):785-91. PMID: 11806977.

FACS IF


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References: 1 entry

Mueller et al. 2002. Blood. 99(3):785-91. PMID: 11806977.

FACS IF


Add a reference

References: 1 entry

Mueller et al. 2002. Blood. 99(3):785-91. PMID: 11806977.

FACS IF


Add a reference


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