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Anti-CEACAM6 (CD66c) [1H7-4B] monoclonal antibody

Invented by Dr Bernhard B. Singer at LeukoCom

Info

Catalogue Number 153324
Applications ELISA FACS IHC WB
Antigen/Gene or Protein Targets CEACAM6, CD66c
Synonyms CD66c
Reactivity Human
Relevance CEACAM6 is a glycosyl phosphatidyl inositol (GPI) linked glycoprotein. CEACAM6 expression is upregulated in many adenocarcinomas and leukemias. CEACAM6 is expressed in epithelial cells of the fetal and adult gastrointestinal tract, epithelia of glandular tissues, squamous epithelial cell of the tongue, esophagus and cervix as well as on granulocytes.
Host Mouse
Immunogen Recombinant human CEACAM6 extracellular domain.
Subclass IgG1 kappa
Molecular Weight (kDa) 90
Myeloma Used P3/NS1/1-Ag4.1
Strain Balb/c
Notes Clone 1H7-4B does not cross-react with human CEACAM1/3/4/5/7/8, rat CECAM1, or mouse CEACAM1/2.
Research Area Immunology

References

There are 6 reference entries for this reagent.

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References: 6 entries

Singer et al. 2014. PLoS One. 9(4):e94106. PMID: 24743304.

Soluble CEACAM8 interacts with CEACAM1 inhibiting TLR2-triggered immune responses.

Europe PMC ID: 24743304

Muturi et al. 2013. PLoS One. 8(9):e74654. PMID: 24040308.

Tumor and endothelial cell-derived microvesicles carry distinct CEACAMs and influence T-cell behavior.

Europe PMC ID: 24040308

Klaile et al. 2013. Respir Res. 14:85. PMID: 23941132.

Carcinoembryonic antigen (CEA)-related cell adhesion molecules are co-expressed in the human lung and their expression can be modulated in bronchial epithelial cells by non-typable Haemophilus influenzae, Moraxella catarrhalis, TLR3, and type I and II int

Europe PMC ID: 23941132


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References: 6 entries

Singer et al. 2014. PLoS One. 9(4):e94106. PMID: 24743304.

Soluble CEACAM8 interacts with CEACAM1 inhibiting TLR2-triggered immune responses.

Muturi et al. 2013. PLoS One. 8(9):e74654. PMID: 24040308.

Tumor and endothelial cell-derived microvesicles carry distinct CEACAMs and influence T-cell behavior.

Klaile et al. 2013. Respir Res. 14:85. PMID: 23941132.

Carcinoembryonic antigen (CEA)-related cell adhesion molecules are co-expressed in the human lung and their expression can be modulated in bronchial epithelial cells by non-typable Haemophilus influenzae, Moraxella catarrhalis, TLR3, and type I and II int


Add a reference