Anti-TNFRSF18 (soluble form) [T10P2H9*B9]
Invented by Ayham Alnabulsi at Vertebrate Antibodies Limited
Catalogue Number | 153188 |
Applications | ELISA IHC WB |
Antigen/Gene or Protein Targets | Tumor Necrosis Factor Receptor Superfamily, Member 18 (TNFRSF18-soluble form), GITR |
Synonyms | Tumor Necrosis Factor Receptor Superfamily Member 18; Glucocorticoid-Induced TNFR-Related Protein; Activation-Inducible TNFR Family Receptor; AITR; GITR; TNF Receptor Superfamily Activation-Inducible Protein; CD357 Antigen; GITR-D; CD357 |
Reactivity | Human |
Relevance | TNFRSF18 is a type I transmembrane protein with homology to members of divergent costimulatory molecules in the TNFRSF. To date three isoforms of TNFRSF18 have been identified, including one soluble form that lacks a transmembrane domain. According to homology of the cytoplasmic domain, TNFRSF18 and other three TNFRSF members (4–1BB, CD27, and OX40) probably constitute a new subfamily as divergent costimulators. TNFRSF18 and the other subfamily members bind TRAF molecules and activate NF-KB. |
Host | Mouse |
Immunogen | Ovalbumin conjugated peptide - PWQQKWVQE |
Subclass | IgG1 kappa |
Formulation | PBS |
Concentration | 1mgml-1 |
Molecular Weight (kDa) | 26 |
Research Area | Cell Signaling & Signal Transduction |
Notes |
The product of the MUC1 gene is the polymorphic epithelial mucin. SM3 reacts with a core protein epitope defined as PDTRP. Recombinant monoclonal antibody produced from the original monoclonal. Manufactured using Absolute Antibody’s Recombinant Platform with variable regions (i.e. specificity) from the hybridoma. *** PLEASE NOTE: Applications stated are those corresponding to original hybridoma ** |
There are 0 reference entries for this reagent.