- References (2)
- Inventor Info
|Applications||ELISA FACS IHC IP WB|
|Antigen/Gene or Protein Targets||Mucin1 (MUC1)|
|Synonyms||ADMCKD, ADMCKD1, Breast carcinoma associated antigen DF3, Breast carcinoma-associated antigen DF3, CA 15-3, CA15 3, CA15 3 antigen, CA15.3, Cancer antigen 15-3, Carcinoma associated mucin, Carcinoma-associated mucin, CD 227, CD227|
|Relevance||Mucin-1 (MUC1) is a membrane protein present on normal human breast epithelial cells and cell lines derived from breast carcinomas. Human MUC1 is also localised on the surface of the human milk fat globule. MUC1 is a differentiation marker and specific breast epithelial marker in normal and neoplastic mammary development. It is upregulated in the lactating breast and in carcinomas.|
|Immunogen||Milk fat globule followed epithelial cells cultured from milk|
|Research Area||Cancer, Cell Type or Organelle Marker, Cell Signaling & Signal Transduction|
Clone also called 3.14.A3 or F314AE11.
The product of the MUC1 gene is the polymorphic epithelial mucin. SM3 reacts with a core protein epitope defined as PDTRP.
Recombinant monoclonal antibody produced from the original monoclonal. Manufactured using Absolute Antibody’s Recombinant Platform with variable regions (i.e. specificity) from the hybridoma.
*** PLEASE NOTE: Applications stated are those corresponding to original hybridoma **
There are 2 reference entries for this reagent.View All References
References: 2 entries
Original hybridoma first published in: Taylor-Papadimitriou et al. 1981. Int J Cancer. 28(1):17-21. PMID: 7309278.
Monoclonal antibodies to epithelium-specific components of the human milk fat globule membrane: production and reaction with cells in culture.
Europe PMC ID: 7309278
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