Cancer Research Technology
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Catalogue Number 153187
Applications ELISA FACS IHC IP WB
Antigen/Gene or Protein Targets Mucin1 (MUC1)
Synonyms ADMCKD, ADMCKD1, Breast carcinoma associated antigen DF3, Breast carcinoma-associated antigen DF3, CA 15-3, CA15 3, CA15 3 antigen, CA15.3, Cancer antigen 15-3, Carcinoma associated mucin, Carcinoma-associated mucin, CD 227, CD227
Reactivity Human
Relevance Mucin-1 (MUC1) is a membrane protein present on normal human breast epithelial cells and cell lines derived from breast carcinomas. Human MUC1 is also localised on the surface of the human milk fat globule. MUC1 is a differentiation marker and specific breast epithelial marker in normal and neoplastic mammary development. It is upregulated in the lactating breast and in carcinomas.
Host Mouse
Immunogen Milk fat globule followed epithelial cells cultured from milk
Subclass IgG1
Formulation PBS
Concentration 1mgml-1
Research Area Cancer, Cell Type or Organelle Marker, Cell Signaling & Signal Transduction
Notes Clone also called 3.14.A3 or F314AE11.

The product of the MUC1 gene is the polymorphic epithelial mucin. SM3 reacts with a core protein epitope defined as PDTRP.
Recombinant monoclonal antibody produced from the original monoclonal. Manufactured using Absolute Antibody’s Recombinant Platform with variable regions (i.e. specificity) from the hybridoma.

*** PLEASE NOTE: Applications stated are those corresponding to original hybridoma **

References: 2 entries

Original hybridoma first published in: Taylor-Papadimitriou et al. 1981. Int J Cancer. 28(1):17-21. PMID: 7309278.

Monoclonal antibodies to epithelium-specific components of the human milk fat globule membrane: production and reaction with cells in culture.

Europe PMC ID: 7309278


Add a reference

References: 2 entries

Original hybridoma first published in: Taylor-Papadimitriou et al. 1981. Int J Cancer. 28(1):17-21. PMID: 7309278.

Monoclonal antibodies to epithelium-specific components of the human milk fat globule membrane: production and reaction with cells in culture.

Europe PMC ID: 7309278


Add a reference

References: 2 entries

Original hybridoma first published in: Taylor-Papadimitriou et al. 1981. Int J Cancer. 28(1):17-21. PMID: 7309278.

Monoclonal antibodies to epithelium-specific components of the human milk fat globule membrane: production and reaction with cells in culture.


Add a reference


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